The role of the human microbiome in the pathogenesis of pain

K Ustianowska, Ł Ustianowski, F Machaj… - International Journal of …, 2022 - mdpi.com
Understanding of the gut microbiome's role in human physiology developed rapidly in recent
years. Moreover, any alteration of this microenvironment could lead to a pathophysiological …

The gut microbiota and chronic pain

R Pak, M Cho, K Pride, A Abd-Elsayed - Current Pain and Headache …, 2024 - Springer
Abstract Purpose of Review To examine the effects and interactions between gut microbia
and chronic pain. Recent Findings The gut microbiome has been an area of interest in both …

Gut microbiota in chronic pain: novel insights into mechanisms and promising therapeutic strategies

L Liu, Q Wu, Y Chen, H Ren, Q Zhang, H Yang… - International …, 2023 - Elsevier
Chronic pain remains one of the world's most persistent and unsolved clinical challenges
that severely affect patients' quality of life. Presently, considering that the mechanisms …

Visceral pain: gut microbiota, a new hope?

MM Pusceddu, MG Gareau - Journal of biomedical science, 2018 - Springer
Background Visceral pain is a complex and heterogeneous disorder, which can range from
the mild discomfort of indigestion to the agonizing pain of renal colic. Regulation of visceral …

Potential roles of gut microbiota and microbial metabolites in chronic inflammatory pain and the mechanisms of therapy drugs

JS Li, SL Su, Z Xu, LH Zhao, RY Fan… - … in Chronic Disease, 2022 - journals.sagepub.com
Observational findings achieved that gut microbes mediate human metabolic health and
disease risk. The types of intestinal microorganisms depend on the intake of food and drugs …

Gut microbiota, immunity and pain

M Santoni, F Miccini, N Battelli - Immunology Letters, 2021 - Elsevier
The interplay between microbiota and nervous system has been associated with a variety of
diseases, including stress, anxiety, depression and cognition. The growing body of …

Microbiota: a novel regulator of pain

M Defaye, S Gervason, C Altier, JY Berthon… - Journal of neural …, 2020 - Springer
Among the various regulators of the nervous system, the gut microbiota has been recently
described to have the potential to modulate neuronal cells activation. While bacteria-derived …

Microbiota and pain: save your gut feeling

C Morreale, I Bresesti, A Bosi, A Baj, C Giaroni… - Cells, 2022 - mdpi.com
Recently, a growing body of evidence has emerged regarding the interplay between
microbiota and the nervous system. This relationship has been associated with several …

[HTML][HTML] Pain regulation by gut microbiota: molecular mechanisms and therapeutic potential

R Guo, LH Chen, C Xing, T Liu - British journal of anaesthesia, 2019 - Elsevier
The relationship between gut microbiota and neurological diseases, including chronic pain,
has received increasing attention. The gut microbiome is a crucial modulator of visceral …

The role of bacteria and its derived metabolites in chronic pain and depression: recent findings and research progress

S Li, D Hua, Q Wang, L Yang, X Wang… - International Journal …, 2020 - academic.oup.com
Background Chronic pain is frequently comorbid with depression in clinical practice.
Recently, alterations in gut microbiota and metabolites derived therefrom have been found …