[HTML][HTML] Generation of a Culex Male Mosquito Sex-Separation RNAi Yeast Strain Using Cas-CLOVER and Super PiggyBac Engineering in Saccharomyces cerevisiae
C Brizzee, K Mysore, TM Njoroge, S McConnell… - Fermentation, 2023 - mdpi.com
Several emerging mosquito control technologies require mass releases of adult male
mosquitoes. Previous studies resulted in the generation of a laboratory female-specific …
mosquitoes. Previous studies resulted in the generation of a laboratory female-specific …
[HTML][HTML] A conserved female-specific larval requirement for MtnB function facilitates sex separation in multiple species of disease vector mosquitoes
K Mysore, L Sun, JB Roethele, P Li, J Igiede… - Parasites & vectors, 2021 - Springer
Background Clusters of sex-specific loci are predicted to shape the boundaries of the M/m
sex-determination locus of the dengue vector mosquito Aedes aegypti, but the identities of …
sex-determination locus of the dengue vector mosquito Aedes aegypti, but the identities of …
[HTML][HTML] A functional requirement for sex-determination M/m locus region lncRNA genes in Aedes aegypti female larvae
K Mysore, LK Hapairai, P Li, JB Roethele, L Sun… - Scientific Reports, 2021 - nature.com
Although many putative long non-coding RNA (lncRNA) genes have been identified in
insect genomes, few of these genes have been functionally validated. A screen for female …
insect genomes, few of these genes have been functionally validated. A screen for female …
Exploring the sex-determination pathway for control of mosquito-borne infectious diseases
Mosquitoes are the vectors of many pathogens that continue to make a large impact on
human health. Current control measures for vector-borne infectious diseases are under …
human health. Current control measures for vector-borne infectious diseases are under …
[HTML][HTML] Molecular tools to create new strains for mosquito sexing and vector control
I Häcker, MF Schetelig - Parasites & vectors, 2018 - Springer
Vector control programs based on population reduction by matings with mass-released
sterile insects require the release of only male mosquitoes, as the release of females, even if …
sterile insects require the release of only male mosquitoes, as the release of females, even if …
Control of mosquito-borne infectious diseases: sex and gene drive
ZN Adelman, Z Tu - Trends in parasitology, 2016 - cell.com
Sterile male releases have successfully reduced local populations of the dengue vector,
Aedes aegypti, but challenges remain in scale and in separating sexes before release. The …
Aedes aegypti, but challenges remain in scale and in separating sexes before release. The …
[HTML][HTML] Silencing the buzz: a new approach to population suppression of mosquitoes by feeding larvae double-stranded RNAs
S Whyard, CNG Erdelyan, AL Partridge, AD Singh… - Parasites & vectors, 2015 - Springer
Background Mosquito-borne diseases threaten over half the world's human population,
making the need for environmentally-safe mosquito population control tools critical. The …
making the need for environmentally-safe mosquito population control tools critical. The …
[HTML][HTML] Mechanisms of sex determination and transmission ratio distortion in Aedes aegypti
Background More effective mosquito control strategies are urgently required due to the
increasing prevalence of insecticide resistance. The sterile insect technique (SIT) and the …
increasing prevalence of insecticide resistance. The sterile insect technique (SIT) and the …
[HTML][HTML] Downregulation of female doublesex expression by oral-mediated RNA interference reduces number and fitness of Anopheles gambiae adult females
ML Taracena, CM Hunt, MQ Benedict… - Parasites & …, 2019 - Springer
Background Mosquito-borne diseases affect millions worldwide, with malaria alone killing
over 400 thousand people per year and affecting hundreds of millions. To date, the best …
over 400 thousand people per year and affecting hundreds of millions. To date, the best …
[HTML][HTML] Joint FAO/IAEA Coordinated Research Project on “Exploring genetic, molecular, mechanical and behavioural methods of sex separation in mosquitoes”–an …
K Bourtzis, ZJ Tu - Parasites & Vectors, 2018 - Springer
Ndo et al.[7] report the isolation, establishment and the characterization of a temperature-
sensitive lethal (tsl) mutant strain in An. arabiensis and describe its potential use for the …
sensitive lethal (tsl) mutant strain in An. arabiensis and describe its potential use for the …