[HTML][HTML] Generation of a Culex Male Mosquito Sex-Separation RNAi Yeast Strain Using Cas-CLOVER and Super PiggyBac Engineering in Saccharomyces cerevisiae

C Brizzee, K Mysore, TM Njoroge, S McConnell… - Fermentation, 2023 - mdpi.com
Several emerging mosquito control technologies require mass releases of adult male
mosquitoes. Previous studies resulted in the generation of a laboratory female-specific …

[HTML][HTML] A conserved female-specific larval requirement for MtnB function facilitates sex separation in multiple species of disease vector mosquitoes

K Mysore, L Sun, JB Roethele, P Li, J Igiede… - Parasites & vectors, 2021 - Springer
Background Clusters of sex-specific loci are predicted to shape the boundaries of the M/m
sex-determination locus of the dengue vector mosquito Aedes aegypti, but the identities of …

[HTML][HTML] A functional requirement for sex-determination M/m locus region lncRNA genes in Aedes aegypti female larvae

K Mysore, LK Hapairai, P Li, JB Roethele, L Sun… - Scientific Reports, 2021 - nature.com
Although many putative long non-coding RNA (lncRNA) genes have been identified in
insect genomes, few of these genes have been functionally validated. A screen for female …

Exploring the sex-determination pathway for control of mosquito-borne infectious diseases

JK Biedler, BA Hall, X Jiang, ZJ Tu - Genetic Control of Malaria and Dengue, 2016 - Elsevier
Mosquitoes are the vectors of many pathogens that continue to make a large impact on
human health. Current control measures for vector-borne infectious diseases are under …

[HTML][HTML] Molecular tools to create new strains for mosquito sexing and vector control

I Häcker, MF Schetelig - Parasites & vectors, 2018 - Springer
Vector control programs based on population reduction by matings with mass-released
sterile insects require the release of only male mosquitoes, as the release of females, even if …

Control of mosquito-borne infectious diseases: sex and gene drive

ZN Adelman, Z Tu - Trends in parasitology, 2016 - cell.com
Sterile male releases have successfully reduced local populations of the dengue vector,
Aedes aegypti, but challenges remain in scale and in separating sexes before release. The …

[HTML][HTML] Silencing the buzz: a new approach to population suppression of mosquitoes by feeding larvae double-stranded RNAs

S Whyard, CNG Erdelyan, AL Partridge, AD Singh… - Parasites & vectors, 2015 - Springer
Background Mosquito-borne diseases threaten over half the world's human population,
making the need for environmentally-safe mosquito population control tools critical. The …

[HTML][HTML] Mechanisms of sex determination and transmission ratio distortion in Aedes aegypti

KP Hoang, TM Teo, TX Ho, VS Le - Parasites & vectors, 2016 - Springer
Background More effective mosquito control strategies are urgently required due to the
increasing prevalence of insecticide resistance. The sterile insect technique (SIT) and the …

[HTML][HTML] Downregulation of female doublesex expression by oral-mediated RNA interference reduces number and fitness of Anopheles gambiae adult females

ML Taracena, CM Hunt, MQ Benedict… - Parasites & …, 2019 - Springer
Background Mosquito-borne diseases affect millions worldwide, with malaria alone killing
over 400 thousand people per year and affecting hundreds of millions. To date, the best …

[HTML][HTML] Joint FAO/IAEA Coordinated Research Project on “Exploring genetic, molecular, mechanical and behavioural methods of sex separation in mosquitoes”–an …

K Bourtzis, ZJ Tu - Parasites & Vectors, 2018 - Springer
Ndo et al.[7] report the isolation, establishment and the characterization of a temperature-
sensitive lethal (tsl) mutant strain in An. arabiensis and describe its potential use for the …