[HTML][HTML] Human genetic polymorphism and Leishmaniasis

K Bharati - Infection, Genetics and Evolution, 2022 - Elsevier
Leishmaniasis is a disease of the subtropical and tropical spheres of the earth and has
various clinical manifestations. The different form of leishmaniasis includes cutaneous …

Genetics and visceral leishmaniasis: of mice and man

JM Blackwell, M Fakiola, ME Ibrahim… - Parasite …, 2009 - Wiley Online Library
Ninety per cent of the 500 000 annual new cases of visceral leishmaniasis (VL) occur in
India/Bangladesh/Nepal, Sudan and Brazil. Importantly, 80–90% of human infections are …

Leishmania and the leishmaniases: a parasite genetic update and advances in taxonomy, epidemiology and pathogenicity in humans

AL Banuls, M Hide, F Prugnolle - Advances in parasitology, 2007 - Elsevier
Leishmaniases remain a major public health problem today despite the vast amount of
research conducted on Leishmania pathogens. The biological model is genetically and …

Genetic susceptibility to leishmanial infections: studies in mice and man

JM Blackwell - Parasitology, 1996 - cambridge.org
Two important recent advances in Leishmania immunology are:(i) the demonstration of a
dramatic dichotomy in T helper 1 versus T helper 2 subset expansion leading to protection …

Candidate gene study of susceptibility to cutaneous leishmaniasis in Sri Lanka

TN Samaranayake, SD Fernando… - Tropical Medicine & …, 2010 - Wiley Online Library
Objectives To investigate the association between selected single nucleotide
polymorphisms (SNPs) in TNF, LTA and SLC11A1 genes and risk of endemic cutaneous …

[HTML][HTML] Human genetics of leishmania infections

JM Blackwell, M Fakiola, LC Castellucci - Human genetics, 2020 - Springer
Identifying genetic risk factors for parasitic infections such as the leishmaniases could
provide important leads for improved therapies and vaccines. Until recently most genetic …

Molecular approaches for a better understanding of the epidemiology and population genetics of Leishmania

G Schönian, K Kuhls, IL Mauricio - Parasitology, 2011 - cambridge.org
Molecular approaches are being used increasingly for epidemiological studies of visceral
and cutaneous leishmaniases. Several molecular markers resolving genetic differences …

Assessment of nuclear and mitochondrial genes in precise identification and analysis of genetic polymorphisms for the evaluation of Leishmania parasites

R Fotouhi-Ardakani, S Dabiri, S Ajdari… - Infection, Genetics and …, 2016 - Elsevier
The polymorphism and genetic diversity of Leishmania genus has status under discussion
depending on many items such as nuclear and/or mitochondrial genes, molecular tools …

Molecular tools for understanding eco-epidemiology, diversity and pathogenesis of Leishmania parasites

S Guerbouj, I Mkada–Driss… - Leishmaniasis—Trends in …, 2014 - books.google.com
Protozoan parasites of the genus Leishmania are responsible of a large variety of clinical
manifestations ranging from self-healing cutaneous forms (CL), through mucocutaneous …

The role of host genetics in leishmaniasis

A Sakthianandeswaren, SJ Foote, E Handman - Trends in parasitology, 2009 - cell.com
Leishmaniasis is one of the world's important infectious diseases. It is prevalent in tropical
and subtropical regions of the world and endemic in 88 countries, with two million new …