[HTML][HTML] Intradermal fractional-dose inactivated polio vaccine (fIPV) adjuvanted with double mutant Enterotoxigenic Escherichia coli heat labile toxin (dmLT) is well …
JW Crothers, ER Colgate, KJ Cowan, DM Dickson… - Vaccine, 2022 - Elsevier
Eradication of poliomyelitis globally is constrained by fecal shedding of live polioviruses,
both wild-type and vaccine-derived strains, into the environment. Although inactivated polio …
both wild-type and vaccine-derived strains, into the environment. Although inactivated polio …
[HTML][HTML] Safety, tolerability, and immunogenicity of inactivated poliovirus vaccine with or without E. coli double mutant heat-labile toxin (dmLT) adjuvant in healthy …
R Erdem, I De Coster, K Withanage, LD Mercer… - Vaccine, 2023 - Elsevier
Background Inactivated trivalent poliovirus vaccine (IPV) induces humoral immunity, which
protects against paralytic poliomyelitis but does not induce sufficient mucosal immunity to …
protects against paralytic poliomyelitis but does not induce sufficient mucosal immunity to …
Inactivated Poliovirus Vaccine: Recent Developments and the Tortuous Path to Global Acceptance
RW Sutter, M Eisenhawer, NA Molodecky, H Verma… - Pathogens, 2024 - mdpi.com
Inactivated poliovirus vaccine (IPV), available since 1955, became the first vaccine to be
used to protect against poliomyelitis. While the immunogenicity of IPV to prevent paralytic …
used to protect against poliomyelitis. While the immunogenicity of IPV to prevent paralytic …
Intestinal immunity to poliovirus following sequential trivalent inactivated polio vaccine/bivalent oral polio vaccine and trivalent inactivated polio vaccine–only …
EB Brickley, W Wieland-Alter, RI Connor… - Clinical Infectious …, 2018 - academic.oup.com
Background Identifying polio vaccine regimens that can elicit robust intestinal mucosal
immunity and interrupt viral transmission is a key priority of the polio endgame. Methods In a …
immunity and interrupt viral transmission is a key priority of the polio endgame. Methods In a …
Polio vaccination: past, present and future
AS Bandyopadhyay, J Garon, K Seib… - Future …, 2015 - Taylor & Francis
Live attenuated oral polio vaccine (OPV) and inactivated polio vaccine (IPV) are the tools
being used to achieve eradication of wild polio virus. Because OPV can rarely cause …
being used to achieve eradication of wild polio virus. Because OPV can rarely cause …
Inactivated and live, attenuated poliovirus vaccines: mucosal immunity
RW Sutter, PA Patriarca - Measles and Poliomyelitis: Vaccines …, 1993 - Springer
Both oral poliovirus vaccine (OPV) and inactivated poliovirus vaccine (IPV). induce some
degree of mucosal immunity. However, OPV-induced mucosal immunity appears similar to …
degree of mucosal immunity. However, OPV-induced mucosal immunity appears similar to …
The long and winding road to eradicate vaccine-related polioviruses
SL Cochi, MA Pallansch - The Journal of infectious diseases, 2021 - academic.oup.com
As the vaccine of choice for the Global Polio Eradication Initiative (GPEI), oral poliovirus
vaccine (OPV) is inexpensive, easy to administer, and can provide good protection against …
vaccine (OPV) is inexpensive, easy to administer, and can provide good protection against …
Poliovirus type 1 systemic humoral and intestinal mucosal immunity induced by monovalent oral poliovirus vaccine, fractional inactivated poliovirus vaccine, and …
CJ Snider, K Zaman, AL Wilkinson, AB Aziz, M Yunus… - Vaccine, 2023 - Elsevier
Background To inform response strategies, we examined type 1 humoral and intestinal
immunity induced by 1) one fractional inactivated poliovirus vaccine (fIPV) dose given with …
immunity induced by 1) one fractional inactivated poliovirus vaccine (fIPV) dose given with …
Intestinal immune responses to type 2 oral polio vaccine (OPV) challenge in infants previously immunized with bivalent OPV and either high-dose or standard …
EB Brickley, CB Strauch… - The Journal of …, 2018 - academic.oup.com
Background The impact of inactivated polio vaccines (IPVs) on intestinal mucosal immune
responses to live poliovirus is poorly understood. Methods In a 2014 phase 2 clinical trial …
responses to live poliovirus is poorly understood. Methods In a 2014 phase 2 clinical trial …
Vaccine-induced mucosal immunity to poliovirus: analysis of cohorts from an open-label, randomised controlled trial in Latin American infants
PF Wright, RI Connor, WF Wieland-Alter… - The Lancet infectious …, 2016 - thelancet.com
Background Identification of mechanisms that limit poliovirus replication is crucial for
informing decisions aimed at global polio eradication. Studies of mucosal immunity induced …
informing decisions aimed at global polio eradication. Studies of mucosal immunity induced …