EIF4A3-induced circBRWD3 promotes tumorigenesis of breast cancer through miR-142-3p_miR-142-5p/RAC1/PAK1 signaling

X Meng, W Li, Z Meng, Y Li - BMC cancer, 2022 - Springer
CircBRWD3 is a newly discovered circRNA, and its potential function has not been probed.
Here, we aimed to molecularly dissect the role of circBRWD3 in the tumorigenesis and …

EIF4A3-induced circZFAND6 promotes breast cancer proliferation and metastasis through the miR-647/FASN axis

X Huang, W Tan, Z Liu, X Fu, Z Li, S Lai, Q Li, X Zhong… - Life Sciences, 2023 - Elsevier
Abstract Aims Circular RNAs (circRNAs) are important regulators in breast cancer
progression. However, the underlying mechanism of circRNAs functions in breast cancer …

CircKDM4B suppresses breast cancer progression via the miR-675/NEDD4L axis

XY Guo, TT Liu, WJ Zhu, HT Liu, GH Zhang, L Song… - Oncogene, 2022 - nature.com
Increasing studies have indicated that circular RNAs (circRNAs) play pivotal roles in various
cancers. Here, we aimed to explore the roles of circRNAs in breast cancer. We identified a …

CircDNAJC11 interacts with TAF15 to promote breast cancer progression via enhancing MAPK6 expression and activating the MAPK signaling pathway

B Wang, H Chen, Y Deng, H Chen, L Xing… - Journal of Translational …, 2023 - Springer
Background Breast cancer (BC) is a common malignant tumor in women worldwide. Circular
RNA (circRNA) has been proven to play a critical role in BC progression. However, the exact …

CircPLK1 sponges miR-296-5p to facilitate triple-negative breast cancer progression

Y Kong, L Yang, W Wei, N Lyu, Y Zou, G Gao, X Ou… - …, 2019 - Taylor & Francis
Aim: To investigate the role of circRNAs in triple-negative breast cancer (TNBC) and the
underlying mechanisms. Materials & methods: We performed circRNA microarrays to …

EIF4A3-mediated circ_0042881 activates the RAS pathway via miR-217/SOS1 axis to facilitate breast cancer progression

C Ju, M Zhou, D Du, C Wang, J Yao, H Li, Y Luo… - Cell Death & …, 2023 - nature.com
Breast cancer (BC) is one of the most frequent cancer-related deaths in women worldwide.
Studies have shown the potential impact of circRNAs in multiple human tumorigeneses …

CircGFRA1 facilitates the malignant progression of HER‐2‐positive breast cancer via acting as a sponge of miR‐1228 and enhancing AIFM2 expression

M Bazhabayi, X Qiu, X Li, A Yang… - Journal of Cellular …, 2021 - Wiley Online Library
CircRNAs (circular RNA) are reported to regulate onset and progress multiple cancers.
Nonetheless, the function along with the underlying mechanisms of circRNAs in HER‐2 …

Up-regulated circBACH2 contributes to cell proliferation, invasion, and migration of triple-negative breast cancer

X Wang, B Xue, Y Zhang, G Guo, X Duan… - Cell Death & Disease, 2021 - nature.com
An increasing amount of evidence has proven the vital role of circular RNAs (circRNAs) in
cancer progression. However, there remains a dearth of knowledge on the function of …

circGNB1 facilitates triple-negative breast cancer progression by regulating miR-141-5p-IGF1R axis

P Liu, Y Zou, X Li, A Yang, F Ye, J Zhang, W Wei… - Frontiers in …, 2020 - frontiersin.org
As an intriguing class of RNA, circular RNAs (circRNAs) are vital mediators of various
diseases including cancers. However, the biological role and underlying mechanism of the …

CircRNA RNF10 inhibits tumorigenicity by targeting miR‐942‐5p/GOLIM4 axis in breast cancer

B Kan, G Yan, Y Shao, Z Zhang… - Environmental and …, 2022 - Wiley Online Library
We aimed to explore the action of a circRNA produced by ring finger protein 10
(circ_RNF10; hsa_circ_0028899) in the malignant behaviors of breast cancer (BC) and to …