[HTML][HTML] Ethnic disparities attributed to the manifestation in and response to type 2 diabetes: insights from metabolomics

S Vasishta, K Ganesh, S Umakanth, MB Joshi - Metabolomics, 2022 - Springer
Abstract Type 2 diabetes (T2D) associated health disparities among different ethnicities
have long been known. Ethnic variations also exist in T2D related comorbidities including …

Metabolomics applied to diabetes− lessons from human population studies

S Liggi, JL Griffin - The international journal of biochemistry & cell biology, 2017 - Elsevier
The 'classical'distribution of type 2 diabetes (T2D) across the globe is rapidly changing and it
is no longer predominantly a disease of middle-aged/elderly adults of western countries, but …

Emerging applications of metabolomic and genomic profiling in diabetic clinical medicine

AM McKillop, PR Flatt - Diabetes Care, 2011 - Am Diabetes Assoc
Clinical and epidemiological metabolomics provides a unique opportunity to look at
genotype-phenotype relationships as well as the body 2019 s responses to environmental …

Microbiome and metabolome dysbiosis analysis in impaired glucose tolerance for the prediction of progression to diabetes mellitus

B Zhang, X Zhang, Z Luo, J Ren, X Yu, H Zhao… - Journal of Genetics and …, 2024 - Elsevier
Gut microbiota and circulating metabolite dysbiosis predate important pathological changes
in glucose metabolic disorders; however, comprehensive studies on impaired glucose …

[HTML][HTML] Uncovering the relationship between gut microbial dysbiosis, metabolomics, and dietary intake in type 2 diabetes mellitus and in healthy volunteers: a multi …

MT Al Bataineh, A Künstner, NR Dash, HS Alsafar… - Scientific Reports, 2023 - nature.com
Abstract Type 2 Diabetes Mellitus has reached epidemic levels globally, and several studies
have confirmed a link between gut microbial dysbiosis and aberrant glucose homeostasis …

[HTML][HTML] Integrated epigenome, whole genome sequence and metabolome analyses identify novel multi-omics pathways in type 2 diabetes: A Middle Eastern study

NA Yousri, OME Albagha, SC Hunt - BMC medicine, 2023 - Springer
Background T2D is of high prevalence in the middle east and thus studying its mechanisms
is of a significant importance. Using 1026 Qatar BioBank samples, epigenetics, whole …

Serum metabolites reflecting gut microbiome alpha diversity predict type 2 diabetes

C Menni, J Zhu, CI Le Roy, O Mompeo, K Young… - Gut …, 2020 - Taylor & Francis
ABSTRACT Type 2 diabetes (T2D) is associated with reduced gut microbiome diversity,
although the cause is unclear. Metabolites generated by gut microbes also appear to be …

Identification of putative biomarkers for type 2 diabetes using metabolomics in the Korea Association REsource (KARE) cohort

HS Lee, T Xu, Y Lee, NH Kim, YJ Kim, JM Kim, SY Cho… - Metabolomics, 2016 - Springer
Abstract Introduction Type 2 diabetes (T2D) is a multifactorial disease resulting from a
complex interaction between environmental and genetic risk factors. Metabolomics provide …

Non-targeted metabolomic biomarkers and metabotypes of type 2 diabetes: A cross-sectional study of PREDIMED trial participants

M Urpi-Sarda, E Almanza-Aguilera, R Llorach… - Diabetes & …, 2019 - Elsevier
Aim To characterize the urinary metabolomic fingerprint and multi-metabolite signature
associated with type 2 diabetes (T2D), and to classify the population into metabotypes …

[HTML][HTML] Genomics and metabolomics in obesity and type 2 diabetes

A Kretowski, FJ Ruperez… - Journal of diabetes …, 2016 - ncbi.nlm.nih.gov
Obesity and associated diseases are responsible for the global burden of morbidity and
mortality, consequently having a huge impact on the economy of healthcare system. Obesity …