Myeloid-derived suppressor cells (MDSCs) are therapeutic agents to prevent graft rejection
in organ transplants by modulating inflammation. Herein, the immunosuppressive effect of …

Background Adoptively transferring different sources of myeloid-derived suppressor cells
(MDSCs) may assist in mice corneal transplant survival. Methods Allogeneic full thickness …

Purpose: To investigate the effects of ex vivo–induced bone marrow myeloid-derived
suppressor cells (BM-MDSCs) on allogeneic immune responses in corneal transplantation …

Purpose To explore the effects of adoptive transferring sepsis induced myeloid-derived
suppressor cells (iMDSCs) in mice corneal, skin, and combined corneal–skin survival …

Highly inflamed and neovascularized corneal graft beds are known as high-risk (HR)
environments for transplant survival. One of the primary factors leading to this rejection is …

Myeloid-derived suppressor cells (MDSC) are one of the major negative regulators of
immune responses during many pathological conditions such as cancer and transplantation …

Purpose: To investigate the effects of intravenous (IV) infusion of human mesenchymal
stem/stromal cells (hMSCs) on activation and migration of CCR7+ antigen presenting cells …

Mesenchymal stem cells (MSCs) are promising candidates for immunomodulatory therapy
that are currently being tested in several organ transplant rejection models. In this study, we …

Investigations into cell therapies for application in organ transplantation have grown. Here,
we describe the ex vivo generation of donor bone marrow–derived dendritic cells (BMDCs) …

We identified the characteristics of myeloid-derived suppressor cells (MDSCs) and
investigated their mechanism of induction and their functional role in allograft rejection using …