[HTML][HTML] Cofilin‑1 as a potential biomarker for Mycobacterium tuberculosis infection

Y Xie, Z Zhang, M Zhang, H Cao - Experimental and …, 2022 - spandidos-publications.com
Tuberculosis (TB) induced by Mycobacterium tuberculosis (M. tb), is one of the deadliest
human infections worldwide. Our previous studies demonstrated cofilin‑1 (CFL1) expression …

[HTML][HTML] Detection of sputum cofilin-1 as indicator of malignancy

MP Rangel, L Antonangelo, MMP Acencio… - Brazilian Journal of …, 2018 - SciELO Brasil
Cofilin-1 (CFL1), a small protein of 18 kDa, has been studied as a biomarker due to its
involvement in tumor cell migration and invasion. Our aim was to evaluate CFL1 as an …

[HTML][HTML] Study of cofilin 1 gene expression in colorectal cancer

S Mousavi, R Safaralizadeh… - Journal of …, 2018 - ncbi.nlm.nih.gov
Background Colorectal cancer (CRC) is one of the most prevalent malignancies worldwide.
Cofilin is a key regulatory protein in the dynamics of actin filaments. Previous studies have …

ESAT-6 of Mycobacterium tuberculosis downregulates cofilin1 and reduces the phagosome acidification in infected macrophages

PP Mahesh, RJ Retnakumar, KC Sivakumar… - bioRxiv, 2020 - biorxiv.org
Mycobacterium tuberculosis when phagocytosed by macrophages is not cleared completely
and many of the bacteria remain in phagosomes indefinitely. In this study we considered …

Cofilin-1 promotes fibrocyte differentiation and contributes to pulmonary fibrosis

W Guo, T Guo, Q Zhou, Y Long, M Luo, Q Shen… - Biochemical and …, 2021 - Elsevier
Fibrocytes originate from the bone marrow monocyte lineage and participate in the
pathogenesis of pulmonary fibrosis. Research providing a comprehensive picture of …

Detection of plasma cofilin protein for diagnosis of lung cancer

Y Zheng, Y Fang, S Li, B Zheng - Nan fang yi ke da xue xue bao …, 2013 - europepmc.org
Objective To detect serum content of cofilin protein in patients with lung cancer and
investigate its clinical value. Methods The serum content of cofilin protein was detected in 30 …

[HTML][HTML] Association of the FCN2 Gene Single Nucleotide Polymorphisms with Susceptibility to Pulmonary Tuberculosis

DD Xu, C Wang, F Jiang, LL Wei, LY Shi, XM Yu… - PLoS …, 2015 - journals.plos.org
Ficolin-2 (FCN2) is an innate immune pattern recognition molecule that can activate the
complement pathway, opsonophagocytosis, and elimination of the pathogens. The present …

[HTML][HTML] The mechanism of cytoskeleton protein β-actin and cofilin-1 of macrophages infected by Mycobacterium avium

J Wang, Y Yao, J Wu, Z Deng, T Gu… - American Journal of …, 2016 - ncbi.nlm.nih.gov
Cytoskeleton proteins and their regulation proteins could be influenced seriously in
Mycobacterium tuberculosis infection host cells leading to the apoptosis of host cells …

The cofilin of host cell and infection--A review

C Zhang, F Chen, L Han - Wei sheng wu xue bao= Acta …, 2015 - europepmc.org
Invasion of pathogens into host cells is the key process to consequently induce the infection,
which depends on the actin cytoskeleton rearrangement. Cofilin in the host cell is one of the …

Differential expression of up-regulated cofilin-1 and down-regulated cofilin-2 characteristic of pancreatic cancer tissues

Y Wang, Y Kuramitsu, T Ueno, N Suzuki… - Oncology …, 2011 - spandidos-publications.com
Pancreatic cancer (PC) is one of the most deadly malignant tumors. The aim of this study
was to identify potential biomarkers for PC. Using two-dimensional gel electrophoresis and …