An update on solid-state characterization of the polyphenol pterostilbene

L Catenacci, M Sorrenti, C Milanese… - Journal of Drug Delivery …, 2022 - Elsevier
The aim of the study was to provide a complete and systematic characterization of the solid-
state properties of the polyphenol pterostilbene (PTB) through an accurate screening of …

The challenge of improving pterostilbene (PTS) solubility for solid and semi-solid dosage forms: The obtention of binary and ternary systems

M Waszczuk, SE Bianchi, V Pittol, S Martiny… - International Journal of …, 2023 - Elsevier
Pterostilbene (PTS) is a drug candidate with low water solubility and poor bioavailability. On
the other hand, drug: cyclodextrins complexes frequently provide bulk powders with low …

A novel, extremely bioavailable cocrystal of pterostilbene

L Bofill, R Barbas, D de Sande… - Crystal Growth & …, 2021 - ACS Publications
New multicomponent solid forms of the nutraceutical pterostilbene have been discovered
and characterized through experimental cocrystal screening. Among the coformers tested …

Amorphous Pterostilbene Delivery Systems Preparation—Innovative Approach to Preparation Optimization

N Rosiak, E Tykarska, J Cielecka-Piontek - Pharmaceutics, 2023 - mdpi.com
The aim of our research was to improve the solubility and antioxidant activity of pterostilbene
(PTR) by developing a novel amorphous solid dispersion (ASD) with Soluplus®(SOL). DSC …

Improving the poor aqueous solubility of nutraceutical compound pterostilbene through cocrystal formation

SJ Bethune, N Schultheiss, JO Henck - Crystal growth & design, 2011 - ACS Publications
Pterostilbene is a nutraceutical compound being investigated for its ability to form cocrystals
with pharmaceutically acceptable coformers to improve its poor aqueous solubility …

Determination of pterostilbene in pharmaceutical products using a new HPLC method and its application to solubility and stability samples

N Haq, F Shakeel, MM Ghoneim, SMB Asdaq, P Alam… - Separations, 2023 - mdpi.com
The quantification of a natural bioactive compound, pterostilbene (PTT), in commercial
capsule dosage form, solubility, and stability samples was carried out using a rapid and …

Nutraceutical cocrystals: utilizing pterostilbene as a cocrystal former

N Schultheiss, S Bethune, JO Henck - CrystEngComm, 2010 - pubs.rsc.org
The nutraceutical compound pterostilbene is investigated for its propensity to form
cocrystalline materials with active pharmaceutical ingredients. Three cocrystals of a 1: 1 …

New stability indicating liquid chromatographic method for the determination of Pterostilbene in capsules

GH Bindu, MM Annapurna - Research Journal of Pharmacy and …, 2018 - indianjournals.com
Pterostilbene is used for the treatment of cancer, diabetes, anti-hyperlipidemic and fungal
infections. A new RP-UFLC method has been developed for the determination of …

Synthesis and Identification of Different Polymorphs of Pitofenone Hydrochloride by FTIR and X-Ray Diffraction Spectrometry

YR Latha - 2009 - search.proquest.com
Polymorphism is defined as the ability of a drug compound to crystallize into more than one
different crystalline form, with different packing arrangements or conformations within the …

Hydrogen bond polarization overcomes unfavorable packing in the most stable high Z′ polymorph of pterostilbene

L Bofill, D de Sande, R Barbas… - Crystal Growth & …, 2019 - ACS Publications
The polymorphic landscape of the nutraceutical pterostilbene has been analyzed by solving
the crystal structure of forms II and III from PXRD data. Polarization effects in the previously …