TGF‐β Signaling: A Recap of SMAD‐independent and SMAD‐dependent Pathways

S Aashaq, A Batool, SA Mir, MA Beigh… - Journal of cellular …, 2022 - Wiley Online Library
Transforming growth factor‐β (TGF‐β) is a proinflammatory cytokine known to control a
diverse array of pathological and physiological conditions during normal development and …

TGF‐β signaling: A tale of two responses

RA Rahimi, EB Leof - Journal of cellular biochemistry, 2007 - Wiley Online Library
Transforming growth factor‐β (TGF‐β) regulates a wide variety of cellular processes
including cell growth, apoptosis, differentiation, migration, and extracellular matrix …

[HTML][HTML] Alterations in the Smad pathway in human cancers

D Samanta, PK Datta - Frontiers in bioscience (Landmark edition), 2012 - ncbi.nlm.nih.gov
Members of the TGF-beta superfamily exhibit various biological activities, and perturbations
of their signaling are linked to certain clinical disorders including cancer. The role of TGF …

TGF-β signalling and its role in cancer progression and metastasis

Y Drabsch, P Ten Dijke - Cancer and Metastasis Reviews, 2012 - Springer
The transforming growth factor-β (TGF-β) system signals via protein kinase receptors and
SMAD mediators to regulate a large number of biological processes. Alterations of the TGF …

TGF-β signal transduction spreading to a wider field: a broad variety of mechanisms for context-dependent effects of TGF-β

H Ikushima, K Miyazono - Cell and tissue research, 2012 - Springer
Transforming growth factor (TGF)-β signaling is involved in almost all major cell behaviors
under physiological and pathological conditions, and its regulatory system has therefore …

TGF-β signaling in cell fate control and cancer

Y Yu, XH Feng - Current opinion in cell biology, 2019 - Elsevier
Members of the transforming growth factor-β (TGF-β) family regulate cell fate decisions
during early embryonic development and tissue homeostasis in the adult. Deregulation of …

Transforming growth factor‐β signaling: tumorigenesis and targeting for cancer therapy

A Ahmadi, M Najafi, B Farhood… - Journal of cellular …, 2019 - Wiley Online Library
Transforming growth factor (TGF)‐β is a multitasking cytokine such that its aberrant
expression is related to cancer progression and metastasis. TGF‐β is produced by a variety …

Biology of transforming growth factor-β signaling

H Ikushima, K Miyazono - Current pharmaceutical …, 2011 - ingentaconnect.com
Transforming growth factor (TGF)-β signaling has been implicated as an important regulator
of almost all major cell behaviors, including proliferation, differentiation, cell death, and …

TGF-β/SMAD signaling and its involvement in tumor progression

K Miyazono - Biological and Pharmaceutical Bulletin, 2000 - jstage.jst.go.jp
抄録 Cytokines of the transforming growth factor-β (TGF-β) superfamily are multifunctional
peptides that regulate growth and differentiation of various types of cells. Members of the …

[HTML][HTML] TGF‑β signaling: A complex role in tumorigenesis

S Liu, S Chen, J Zeng - Molecular medicine reports, 2018 - spandidos-publications.com
Tumor progression can be affected by various cellular components of tumor cells and/or by
tumor microenvironmental factors. The tumor microenvironment comprises a variety of …