Recent progress toward the implementation of phage therapy in Western medicine

JP Pirnay, T Ferry, G Resch - FEMS microbiology reviews, 2022 - academic.oup.com
Like the sword of Damocles, the threat of a post-antibiotic era is hanging over humanity's
head. The scientific and medical community is thus reconsidering bacteriophage therapy …

[HTML][HTML] Bacteriophage therapy: Developments and directions

MP Nikolich, AA Filippov - Antibiotics, 2020 - mdpi.com
In an era of proliferating multidrug resistant bacterial infections that are exhausting the
capacity of existing chemical antibiotics and in which the development of new antibiotics is …

Phage therapy: Current status and perspectives

A Górski, R Międzybrodzki, G Węgrzyn… - Medicinal research …, 2020 - Wiley Online Library
The spread of antimicrobial resistant bacterial pathogens combined with the lack of new
drug classes in the antibiotic pipeline causes a resurgence of the use of bacterial viruses …

[HTML][HTML] Bacteriophage therapy: clinical trials and regulatory hurdles

LL Furfaro, MS Payne, BJ Chang - Frontiers in cellular and infection …, 2018 - frontiersin.org
Increasing reports of antimicrobial resistance and limited new antibiotic discoveries and
development have fuelled innovation in other research fields and led to a revitalization of …

Re-establishing a place for phage therapy in western medicine

EM Kutter, SJ Kuhl, ST Abedon - Future microbiology, 2015 - Future Medicine
Use of bacterial viruses as antibacterial agents has a history nearly as long as the now 100-
year study of bacteriophages. Therapeutic phages are especially useful in the absence of …

[HTML][HTML] Current clinical landscape and global potential of bacteriophage therapy

NM Hitchcock, D Devequi Gomes Nunes, J Shiach… - Viruses, 2023 - mdpi.com
In response to the global spread of antimicrobial resistance, there is an increased demand
for novel and innovative antimicrobials. Bacteriophages have been known for their potential …

[HTML][HTML] Phage therapy: combating infections with potential for evolving from merely a treatment for complications to targeting diseases

A Górski, R Międzybrodzki… - Frontiers in …, 2016 - frontiersin.org
Antimicrobial resistance is considered to be one of the greatest challenges of medicine and
our civilization. Lack of progress in developing new anti-bacterial agents has greatly revived …

[HTML][HTML] Translating phage therapy into the clinic: recent accomplishments but continuing challenges

A Petrovic Fabijan, J Iredell, K Danis-Wlodarczyk… - Plos …, 2023 - journals.plos.org
Phage therapy is a medical form of biological control of bacterial infections, one that uses
naturally occurring viruses, called bacteriophages or phages, as antibacterial agents …

[HTML][HTML] Bacteriophages as alternatives to antibiotics in clinical care

D Romero-Calle, R Guimarães Benevides… - Antibiotics, 2019 - mdpi.com
Antimicrobial resistance is increasing despite new treatments being employed. With a
decrease in the discovery rate of novel antibiotics, this threatens to take humankind back to …

[HTML][HTML] Bacteriophage Therapy for Difficult-to-Treat Infections: The Implementation of a Multidisciplinary Phage Task Force (The PHAGEFORCE Study Protocol)

J Onsea, S Uyttebroek, B Chen, J Wagemans, C Lood… - Viruses, 2021 - mdpi.com
In times where only a few novel antibiotics are to be expected, antimicrobial resistance
remains an expanding global health threat. In case of chronic infections caused by therapy …