Targeted therapy in the management of modern craniopharyngiomas

M Reyes, M Taghvaei, S Yu, A Sathe, S Collopy… - 2022 - jdc.jefferson.edu
Background: The proximity of craniopharyngiomas (CPs) to critical neurovascular structures
can lead to a host of neurologic and endocrine complications that lead to difficulty with …

Can tissue biomarkers reliably predict the biological behavior of craniopharyngiomas? A comprehensive overview

R Prieto, JM Pascual - Pituitary, 2018 - Springer
Background The growing interest in the molecular and genetic alterations of
craniopharyngiomas (CPs) is embodied in recent studies revealing insights into the CP …

Potential evolution of neurosurgical treatment paradigms for craniopharyngioma based on genomic and transcriptomic characteristics

LC Robinson, S Santagata, TC Hankinson - Neurosurgical Focus, 2016 - thejns.org
The recent genomic and transcriptomic characterization of human craniopharyngiomas has
provided important insights into the pathogenesis of these tumors and supports that these …

Contemporary biological insights and clinical management of craniopharyngioma

JR Apps, HL Muller, TC Hankinson, TI Yock… - Endocrine …, 2023 - academic.oup.com
Craniopharyngiomas (CPs) are clinically aggressive tumors because of their invasive
behavior and recalcitrant tendency to recur after therapy. There are 2 types based on their …

[HTML][HTML] Medical therapy for craniopharyngiomas

KI Alexandraki, P Xekouki - touchREVIEWS in Endocrinology, 2021 - ncbi.nlm.nih.gov
Craniopharyngiomas are rare benign neoplasms presenting in two different types,
adamantinomatous (ACP) or papillary (PCP), which are molecularly and clinically distinct …

Craniopharyngioma: a roadmap for scientific translation

S Gupta, WL Bi, AG Larsen, S Al-Abdulmohsen… - Neurosurgical …, 2018 - thejns.org
OBJECTIVE Craniopharyngiomas are among the most challenging of intracranial tumors to
manage because of their pattern of growth, associated morbidities, and high recurrence rate …

Targeted therapies in the medical management of craniopharyngioma

P Iglesias - Pituitary, 2022 - Springer
Craniopharyngioma (CP) is an intracranial benign tumor that behaves aggressively due to
its location, infiltration of the surrounding nervous tissue and high capacity for recurrence …

Integrating Systemic Therapies into the Multimodality Therapy of Patients with Craniopharyngioma

D Gritsch, S Santagata, PK Brastianos - Current Treatment Options in …, 2024 - Springer
Opinion statement The integration of targeted therapy into the multimodal management of
craniopharyngiomas represents a significant advancement in the field of neuro-oncology …

[HTML][HTML] Advancing Craniopharyngioma Management: A Systematic Review of Current Targeted Therapies and Future Perspectives

E Agosti, M Zeppieri, S Antonietti, A Piazza… - International Journal of …, 2024 - mdpi.com
Craniopharyngiomas present unique challenges in surgical management due to their
proximity to critical neurovascular structures. This systematic review investigates genetic and …

[HTML][HTML] Genetic and immune profiling for potential therapeutic targets in adult human craniopharyngioma

C Kassab, D Zamler, C Kamiya-Matsuoka… - Clinical oncology and …, 2019 - ncbi.nlm.nih.gov
Craniopharyngioma is a rare tumor in adults. Although histologically benign, it can be locally
aggressive and may require additional therapeutic modalities to surgical resection. Analyses …