The brain exhibits distinct patterns of recurrent activity closely related to behavioral state.
The neural mechanisms that underlie state-dependent activity in the awake animal are …

Spontaneous and sensory-evoked cortical activity is highly state-dependent, yet relatively
little is known about transitions between distinct waking states. Patterns of activity in mouse …

During inattentive wakefulness and non-rapid eye movement (NREM) sleep, the neocortex
and thalamus cooperatively engage in rhythmic activities that are exquisitely reflected in the …

The thalamus controls transmission of sensory signals from periphery to cortex, ultimately
shaping perception. Despite this significant role, dynamic thalamic gating and the …

We investigated the impact of thalamus on ongoing cortical activity in the awake, behaving
mouse. We demonstrate that the desynchronized cortical state during active behavior is …

Slow waves represent one of the prominent EEG signatures of non-rapid eye movement
(non-REM) sleep and are thought to play an important role in the cellular and network …

We show for the first time with in vitro recording that burst firing in thalamic relay cells of the
monkey is evoked by activation of voltage-dependent, low threshold Ca2+ spikes (LTSs), as …

Abstract Slow waves (0.5–4 Hz) predominate in the cortical electroencephalogram during
non-rapid eye movement (NREM) sleep in mammals. They reflect the synchronization of …

Ongoing changes in arousal influence sensory processing and behavioral performance. Yet
the circuit-level correlates for this influence remain poorly understood. Here, we investigate …

Low-frequency membrane potential (V m) oscillations were once thought to only occur in
sleeping and anesthetized states. Recently, low-frequency V m oscillations have been …