Long non-coding RNAs: novel regulators of cellular physiology and function
JA Oo, RP Brandes, MS Leisegang - Pflügers Archiv-European Journal of …, 2022 - Springer
Long non-coding RNAs were once considered as “junk” RNA produced by aberrant DNA
transcription. They are now understood to play central roles in diverse cellular processes …
transcription. They are now understood to play central roles in diverse cellular processes …
Roles for long non-coding RNAs in physiology and disease
MT Melissari, P Grote - Pflügers Archiv-European Journal of Physiology, 2016 - Springer
While the vast majority of the genome is transcribed into RNA, only a small fraction of these
transcripts have protein-coding potential. A large fraction of the transcribed RNA belongs to …
transcripts have protein-coding potential. A large fraction of the transcribed RNA belongs to …
[HTML][HTML] Gene regulation by long non-coding RNAs and its biological functions
Evidence accumulated over the past decade shows that long non-coding RNAs (lncRNAs)
are widely expressed and have key roles in gene regulation. Recent studies have begun to …
are widely expressed and have key roles in gene regulation. Recent studies have begun to …
Long noncoding RNA: genomics and relevance to physiology
The mammalian cell expresses thousands of long noncoding RNAs (lncRNAs) that are
longer than 200 nucleotides but do not encode any protein. lncRNAs can change the …
longer than 200 nucleotides but do not encode any protein. lncRNAs can change the …
Molecular functions and biological roles of long non‐coding RNAs in human physiology and disease
F Kopp - The journal of gene medicine, 2019 - Wiley Online Library
The human genome has been demonstrated to be pervasively transcribed, with a large
fraction of the transcriptome representing non‐protein‐coding RNA species. A relatively …
fraction of the transcriptome representing non‐protein‐coding RNA species. A relatively …
Besides pathology: long non-coding RNA in cell and tissue homeostasis
A Salviano-Silva, SC Lobo-Alves, RC Almeida… - Non-coding RNA, 2018 - mdpi.com
A significant proportion of mammalian genomes corresponds to genes that transcribe long
non-coding RNAs (lncRNAs). Throughout the last decade, the number of studies concerning …
non-coding RNAs (lncRNAs). Throughout the last decade, the number of studies concerning …
Long noncoding RNAs: lincs between human health and disease
ZH Kwok, Y Tay - Biochemical Society Transactions, 2017 - portlandpress.com
Long noncoding RNAs (lncRNAs) represent one of the largest classes of transcripts and are
highly diverse in terms of characteristics and functions. Advances in high-throughput …
highly diverse in terms of characteristics and functions. Advances in high-throughput …
Mechanisms of long noncoding RNA function in development and disease
SU Schmitz, P Grote, BG Herrmann - Cellular and molecular life sciences, 2016 - Springer
Since decades it has been known that non-protein-coding RNAs have important cellular
functions. Deep sequencing recently facilitated the discovery of thousands of novel …
functions. Deep sequencing recently facilitated the discovery of thousands of novel …
Long noncoding RNA: its physiological and pathological roles
B Yan, Z Wang - DNA and Cell Biology, 2012 - liebertpub.com
Long noncoding RNAs (lncRNAs) are transcribed RNA molecules> 200 nucleotides in
length. They comprise a diverse class of transcripts that structurally resemble mRNAs, but do …
length. They comprise a diverse class of transcripts that structurally resemble mRNAs, but do …
Physiological roles of long noncoding RNAs: insight from knockout mice
Long noncoding RNAs (lncRNAs) are a pervasive and recently recognized class of genes.
lncRNAs have been proposed to modulate gene expression and nuclear architecture, but …
lncRNAs have been proposed to modulate gene expression and nuclear architecture, but …