Illuminating chromatin organization at nuclear landmarks using chemical genomics

SA Roseman - 2023 - search.proquest.com
The three-dimensional conformation of chromatin is key to regulating gene expression and
maintaining cell states. Protein cofactors are essential for the formation and maintenance of …

Development and Application of Software to Understand 3D Chromatin Structure and Gene Regulation

ES Davis - 2023 - search.proquest.com
Nearly all cells contain the same 2 meters of DNA that must be systematically organized into
their nucleus for timely access to genes in response to stimuli. Proteins and biomolecular …

[PDF][PDF] Single-molecule investigations of isolated cohesin domains

M Freitag - 2023 - edoc.ub.uni-muenchen.de
The inheritance of genetic information depends on the duplication and transfer of
deoxyribonucleic acid (DNA) molecules from parental cells to daughter cells (1). Therefore …

Titration of oncogenic RAS alters senescent state and influences tumour initiation

M Narita, A Chan, H Zhu, M Narita, L Cassidy, A Young… - 2023 - researchsquare.com
Oncogenic RAS-induced senescence (OIS) is an autonomous tumour suppressor
mechanism associated with pre-malignancy 1-3. Achieving this phenotype typically requires …

frontiers REVIEW in Cell and Developmental Biology published: 24 November 2021

C Das, A Shukla, S Shukla, R Taneja… - … Pathways in Cancer …, 2023 - books.google.com
The immune system protects the human body from different infections and can respond to
cellular damage. Chiefly, the immune system plays a central role in clearing infection …