Mass spectrometry for mitochondrial multi-omics
Mitochondria are highly dynamic organelles involved in many aspects of cell metabolism.
Mitochondrial dysfunction is linked to various disorders, including neurodegenerative …
Mitochondrial dysfunction is linked to various disorders, including neurodegenerative …
A big picture of the mitochondria-mediated signals: From mitochondria to organism
NV Acar, RK Özgül - Biochemical and Biophysical Research …, 2023 - Elsevier
Mitochondria, well-known for years as the powerhouse and biosynthetic center of the cell,
are dynamic signaling organelles beyond their energy production and biosynthesis …
are dynamic signaling organelles beyond their energy production and biosynthesis …
线粒体逆行信号在肿瘤进展中的研究现状
许小君, 廖达文, 王星琛, 魏元元, 黄启超, 杜钰璐 - 中国癌症防治杂志, 2023 - zgazfz.com
线粒体是细胞进行有氧呼吸的主要场所, 被誉为细胞的动力工厂. 除了供能,
线粒体还可作为信号转导中心在调控细胞生理功能及疾病发生等过程发挥重要作用. 例如 …
线粒体还可作为信号转导中心在调控细胞生理功能及疾病发生等过程发挥重要作用. 例如 …
Importance of lactate dehydrogenase (LDH) and monocarboxylate transporters (MCTs) in cancer cells
H Hatami, A Sajedi, SM Mir… - Health Science Reports, 2023 - Wiley Online Library
Background In most regions, cancer ranks the second most frequent cause of death
following cardiovascular disorders. Aim In this article, we review the various aspects of …
following cardiovascular disorders. Aim In this article, we review the various aspects of …
A mathematically rigorous algorithm to define, compute and assess relevance of the probable dissociation constant for every reaction of a constrained biochemical …
S Kundu - 2023 - researchsquare.com
Metabolism is a combination of enzymatic-and non-enzymatic interactions of several macro-
and small-molecules and occurs via biochemical networks. Here, we present a …
and small-molecules and occurs via biochemical networks. Here, we present a …
A targeted metabolomic method to detect epigenetically relevant metabolites
J Miro-Blanch, A Junza, J Capellades, A Balvay… - bioRxiv, 2023 - biorxiv.org
Metabolites play a central role in the chemical crosstalk between metabolism and epigenetic
marks. Epigenetically relevant metabolites are substrates, products and cofactors that can …
marks. Epigenetically relevant metabolites are substrates, products and cofactors that can …
Chromatin states contribute to coordinated allelic transcriptional bursting to drive iPSC reprogramming
A Parichitran, HC Naik, AJ Naskar, LS Bammidi… - bioRxiv, 2023 - biorxiv.org
Molecular mechanisms behind the reprogramming of somatic cells to induced pluripotent
stem cells (iPSC) remain poorly understood. While dynamic changes in gene expression are …
stem cells (iPSC) remain poorly understood. While dynamic changes in gene expression are …
[HTML][HTML] A cuproptosis-related signature for predicting the prognosis of gastric cancer
C He, H Zhang, Z Guo, Z Mo - Journal of Gastrointestinal Oncology, 2023 - ncbi.nlm.nih.gov
Background Gastric cancer (GC) is one of the most common malignancies. Cuproptosis is a
newly discovered type of cell death caused by protein toxicity stress, with copper having …
newly discovered type of cell death caused by protein toxicity stress, with copper having …
Macrophage memory: Types, Mechanisms, and Its Role in Health and Disease
AH Liao, XH Fang, ZJ Li, CY Liu, G Mor - Authorea Preprints, 2023 - authorea.com
On the basis of the mechanisms of action and characteristics of immune effects, immunity is
generally divided into innate and adaptive immunity. Adaptive immunity is associated with …
generally divided into innate and adaptive immunity. Adaptive immunity is associated with …
Metabolic dependencies of metastasis-initiating cells in breast cancer
CMT Young - 2023 - infoscience.epfl.ch
Metastasis is the process by which cancer cells from the primary tumor travel through the
blood stream to generate a secondary tumor site in a distant organ. Although very few cells …
blood stream to generate a secondary tumor site in a distant organ. Although very few cells …