[HTML][HTML] Abnormal glycosylation in glioma: related changes in biology, biomarkers and targeted therapy
J Yue, R Huang, Z Lan, B Xiao, Z Luo - Biomarker Research, 2023 - Springer
Glioma is a rapidly growing and aggressive primary malignant tumor of the central nervous
system that can diffusely invade the brain tissue around, and the prognosis of patients is not …
system that can diffusely invade the brain tissue around, and the prognosis of patients is not …
[HTML][HTML] Clinically relevant glioblastoma patient-derived xenograft models to guide drug development and identify molecular signatures
J Alcaniz, L Winkler, M Dahlmann, M Becker… - Frontiers in …, 2023 - frontiersin.org
Glioblastoma (GBM) heterogeneity, aggressiveness and infiltrative growth drastically limit
success of current standard of care drugs and efficacy of various new therapeutic …
success of current standard of care drugs and efficacy of various new therapeutic …
[HTML][HTML] Mitoepigenetics and gliomas: epigenetic alterations to mitochondrial DNA and nuclear DNA alter mtDNA expression and contribute to glioma pathogenicity
Epigenetic mechanisms allow cells to fine-tune gene expression in response to
environmental stimuli. For decades, it has been known that mitochondria have genetic …
environmental stimuli. For decades, it has been known that mitochondria have genetic …
[HTML][HTML] Author Correction: Federated learning enables big data for rare cancer boundary detection
Author Correction: Federated learning enables big data for rare cancer boundary detection |
Nature Communications Skip to main content Thank you for visiting nature.com. You are using …
Nature Communications Skip to main content Thank you for visiting nature.com. You are using …
Investigational treatment strategies in glioblastoma: progress made and barriers to success
TA Nelson, J Dietrich - Expert opinion on investigational drugs, 2023 - Taylor & Francis
Introduction Glioblastoma, isocitrate dehydrogenase wildtype (IDHwt), remains an incurable
disease despite considerable research effort. The current standard of care since 2005 …
disease despite considerable research effort. The current standard of care since 2005 …
[HTML][HTML] Single-cell RNA sequencing reveals changes in glioma-associated macrophage polarization and cellular states of malignant gliomas with high AQP4 …
R Wang, L Peng, Y Xiao, Q Zhou, Z Wang, L Tang… - Cancer gene …, 2023 - nature.com
Glioma is the most common primary central nervous system tumor in adults. Aquaporin-4, as
a water channel protein encoded by AQP4 in the brain, is reported to alter its aggregation …
a water channel protein encoded by AQP4 in the brain, is reported to alter its aggregation …
Prognosis prediction for glioblastoma multiforme patients using machine learning approaches: Development of the clinically applicable model
Background and purpose We aimed to develop a clinically applicable prognosis prediction
model predicting overall survival (OS) and progression-free survival (PFS) for glioblastoma …
model predicting overall survival (OS) and progression-free survival (PFS) for glioblastoma …
[HTML][HTML] Pericyte–glioblastoma cell interaction: A key target to prevent glioblastoma progression
A Pombero, R Garcia-Lopez, S Martínez - Cells, 2023 - mdpi.com
Multiple biological processes rely on direct intercellular interactions to regulate cell
proliferation and migration in embryonic development and cancer processes. Tumor …
proliferation and migration in embryonic development and cancer processes. Tumor …
[HTML][HTML] Characteristics of vasculogenic mimicry and tumour to endothelial transdifferentiation in human glioblastoma: a systematic review
Background Glioblastoma, the most common primary malignant brain tumour in adults, is a
highly vascular tumour characterised by abnormal angiogenesis. Additional mechanisms of …
highly vascular tumour characterised by abnormal angiogenesis. Additional mechanisms of …
[HTML][HTML] Antiangiogenic therapy for malignant brain tumors: does it still Matter?
A Pellerino, F Bruno, R Soffietti, R Rudà - Current Oncology Reports, 2023 - Springer
Abstract Purpose of Review To summarize the mechanisms of tumor angiogenesis and
resistance to antiangiogenic therapy, and the influence on tumor microenvironment. Recent …
resistance to antiangiogenic therapy, and the influence on tumor microenvironment. Recent …