Multicellular network-informed survival model for identification of drug targets of gliomas

X He, X Sun, Y Shao - IEEE Journal of Biomedical and Health …, 2023 - ieeexplore.ieee.org
Increasing evidence suggests that communication between tumor cells (TCs) and tumor-
associated macrophages (TAMs) plays a substantial role in promoting progression of low …

Clinical Significance of Early Venous Filling Detected via Preoperative Angiography in Glioblastoma

K Tatebayashi, N Nakayama, D Sakamoto, T Iida… - Cancers, 2023 - mdpi.com
Simple Summary Our study examined early venous filling (EVF) on angiography, a potential
sign of aggressiveness in a type of brain cancer known as glioblastoma (GBM). The study …

[HTML][HTML] Health-related quality-of-life results from the randomised phase II TAVAREC trial on temozolomide with or without bevacizumab in 1p/19q intact first …

JC Reijneveld, A Machingura, C Coens… - European Journal of …, 2023 - Elsevier
Background In an international randomised controlled phase II study of temozolomide (TMZ)
versus TMZ in combination with bevacizumab (BEV) in locally diagnosed non-1p/19q co …

Effects of postoperative intravenous cyclosporine treatment on the survival and functional performance status of patients with glioblastoma: a randomized, triple …

M Shafizadeh, F Farzaneh, SB Kankam, E Jangholi… - World Neurosurgery, 2023 - Elsevier
Background Glioblastoma is associated with low median survival time irrespective of
maximal treatment. Previous in vitro studies have revealed tumor inhibitory effect of …

Advances in blood–brain barrier-crossing nanomedicine for anti-glioma

D Liu, X Dai, Z Tao, H Zhou, W Hong, H Qian… - Cancer …, 2023 - Springer
Glioma is the most prevalent type of primary brain tumor, and glioblastoma multiforme (GBM)
is the highest and most deadly type of primary central nervous system (CNS) tumor, affecting …

Current and promising treatment strategies in glioma

P Śledzińska, M Bebyn, J Furtak, A Koper… - Reviews in the …, 2023 - degruyter.com
Gliomas are the most common primary central nervous system tumors; despite recent
advances in diagnosis and treatment, glioma patients generally have a poor prognosis …

Advances in Treatment of Isocitrate Dehydrogenase (IDH)-Wildtype Glioblastomas

HW Sim, S Lorrey, M Khasraw - Current Neurology and Neuroscience …, 2023 - Springer
Abstract Purpose of Review The management of isocitrate dehydrogenase (IDH)-wildtype
glioblastomas is an area of unmet need. Despite multimodal therapy incorporating maximal …

Immunological and tumor-intrinsic mechanisms mediate the synergistic growth suppression of experimental glioblastoma by radiotherapy and MET inhibition

M Silginer, E Papa, E Szabó, F Vasella… - Acta Neuropathologica …, 2023 - Springer
The hepatocyte growth factor (HGF)/MET signaling pathway has been proposed to be
involved in the resistance to radiotherapy of glioblastoma via proinvasive and DNA damage …

[HTML][HTML] Preclinical and early clinical studies of a novel compound SYHA1813 that efficiently crosses the blood–brain barrier and exhibits potent activity against …

Y Liu, Z Zhan, Z Kang, M Li, Y Lv, S Li, L Tong… - … Pharmaceutica Sinica B, 2023 - Elsevier
Glioblastoma (GBM) is the most common and aggressive malignant brain tumor in adults
and is poorly controlled. Previous studies have shown that both macrophages and …

Assessment of the specificity and stability of Micro-RNAs as a forensic gene marker

YH Al-Mawlah, HM Asma'a… - Biomedical and …, 2023 - journals.lww.com
Background: Forensic investigations depend on bodily fluid analysis to identify the
perpetrators. Identifying perpetrators requires knowledge about suspects' body fluids. Due to …