Protein lysine acetylation refers to the covalent transfer of an acetyl moiety from acetyl
coenzyme A to the epsilon‐amino group of a lysine residue and is critical for regulating …

Proteins are functionally regulated by various types of posttranslational modifications
(PTMs). Ku, a heterodimer complex of Ku70 and Ku80 subunits, participates in DNA repair …

Sirtuins are NAD+-dependent deacetylases with beneficial roles in conditions relevant to
human health, including metabolic disease, type II diabetes, obesity, cancer, aging …

Mammalian oocyte maturation relies on mitochondrial ATP production, but this can lead to
damaging reactive oxygen species (ROS). SIRT3, a mitochondrial sirtuin, plays a critical role …

The cardiac proteome has a vast number of gene products that are post-translationally
modified (PTM). PTMs are essential for the regulation of normal excitation–contraction …

Abstract Nonalcoholic Fatty Liver Disease (NAFLD) is a progressive liver disease that can
lead to liver cirrhosis and hepatocellular carcinoma, eventually resulting in death. The …

Mycobacterium tuberculosis (M. tb) is an airborne infectious agent that causes tuberculosis
(TB). The Bacillus Calmette-Guérin (BCG) vaccine is utilized to provide anti-TB immunity …

Post-translational modifications (PTMs) of proteins define the molecular complexity of our
cells. Through mechanisms such as covalent modifications of proteins, PTMs change the …

This chapter introduces the biosynthetic pathways that lead to the generation of acetyl-CoA
and its use as donor of the acetyl group in the reaction of protein and ganglioside …

El citocromo c es una proteína pequeña y globular cuya función principal consiste en actuar
como un transportador electrónico móvil entre los complejos III y IV de la cadena de …