In neurology and psychiatry, recent advances by PET have yielded unprecedented insights
into the functioning of the human brain and the development of novel treatment strategies. 1 …

Background: Alzheimer's disease (AD), the primary cause of dementia, escalating
worldwide, has no proper diagnosis or effective treatment. Neuronal cell death and …

With the advances in modern medicine and the adaptation towards healthier lifestyles, the
average life expectancy has doubled since the 1930s, with individuals born in the …

Purpose Measuring longitudinal changes in amyloid load in the asymptomatic stage of
Alzheimer's disease is of high relevance for clinical research and progress towards more …

Traumatic brain injury (TBI) has been discussed as a risk factor for Alzheimer's disease (AD)
due to its association with dementia risk and earlier cognitive symptom onset. However, the …

Positron emission tomography (PET) imaging with radiotracers that bind to fibrillary amyloid
β (Aβ) deposits is an important tool for the diagnosis of Alzheimer's disease (AD) and for the …

阿尔茨海默病(AD) 是一种好发于老年人的神经退行性疾病, 是痴呆最常见的原因,
发病隐匿且临床表现缺乏特异性, 早期诊断困难. 目前, 基于生物标志物的AT (N) 诊断框架使AD …

Diagnosis of Alzheimer's disease (AD) is crucial especially for the complete comprehension
of pathology and clinical therapy of the disorder, as well as in declining the severity of the …

Background 18 F-florbetaben (FBB) positron emission tomography (PET) scan has been
widely used in research and routine clinical practice. Most studies used late-phase …

The standardized uptake value ratio (SUVR) is used to measure Aβ uptake in PET images of
the brain. Variations in PET scanner technologies and image reconstruction techniques can …