Topical tranexamic acid in breast reconstruction: A double-blind randomized controlled trial

T Safran, J Vorstenbosch… - Plastic and …, 2023 - journals.lww.com
Background: Excess fluid accumulation (seroma/hematoma) around the breast implant after
reconstruction can lead to significant complications. Topical administration of tranexamic …

When to use tranexamic acid for the treatment of major bleeding?

ZK McQuilten, EM Wood, RL Medcalf - Journal of Thrombosis and …, 2023 - Elsevier
Tranexamic acid (TXA) is an anti-fibrinolytic agent originally developed for the management
of bleeding in the setting of post-partum hemorrhage (PPH). Over the last 15 years, there …

[HTML][HTML] Analysis of the efficacy of prophylactic tranexamic acid in preventing postpartum bleeding: systematic review with meta-analysis of randomized clinical trials

IC Assis, CS Govêia, DB Miranda… - Brazilian Journal of …, 2023 - SciELO Brasil
Abstract Background Postpartum Hemorrhage (PPH) is one of the main causes of maternal
mortality, mainly in the poorest regions of the world, drawing attention to the need for …

Tranexamic acid in burn surgery: A systematic review and meta-analysis

AJ Fijany, KB Givechian, I Zago, SE Olsson, MJ Boctor… - Burns, 2023 - Elsevier
Burn injury causes a coagulopathy that is poorly understood. After severe burns, significant
fluid losses are managed by aggressive resuscitation that can lead to hemodilution. These …

Tranexamic acid is not associated with decreased infection risk after primary shoulder arthroplasty: a cohort study of 9276 patients

J Gorbaty, PH Chan, MD McElvany, HA Prentice… - Journal of Shoulder and …, 2023 - Elsevier
Background The use of tranexamic acid (TXA) is associated with less blood loss and
reduced transfusion risk after shoulder arthroplasty surgery. Recent studies have shown …

The effects of timing of prehospital tranexamic acid on outcomes after traumatic brain injury: subanalysis of a randomized controlled trial

AMP Brito, MA Schreiber, J El Haddi… - Journal of trauma and …, 2023 - journals.lww.com
BACKGROUND Tranexamic acid (TXA) is an antifibrinolytic that has shown some promise in
improving outcomes in traumatic brain injury (TBI), but only when given early after injury. We …

Development of a national out-of-hospital transfusion protocol: a modified RAND Delphi study

J von Vopelius-Feldt, J Lockwood, S Mal… - … Open Access Journal, 2023 - cmajopen.ca
Background: Early resuscitation with blood components or products is emerging as best
practice in selected patients with trauma and medical patients; as a result, out-of-hospital …

Maintaining the Balance: The Critical Role of Plasmin Activity in Orthopaedic Surgery Injury Response

SN Moore-Lotridge, KS Hajdu, BQ Hou… - Journal of Thrombosis …, 2023 - Elsevier
The musculoskeletal system plays vital roles in the body, facilitating movement, protecting
vital structures, and regulating hematopoiesis and mineral metabolism. Injuries to this …

Physician-staffed prehospital units: a retrospective follow-up from an urban area in Scandinavia

E Strandqvist, S Olheden, A Bäckman… - International Journal of …, 2023 - Springer
Background The aim of this study was to determine when and how rapid response vehicles
(RRVs) make a difference in prehospital care by investigating the number and kinds of RRV …

Does infection play a role in post-tonsillectomy haemorrhage? A narrative review

A Williamson, H Coleman, C Douglas - The Journal of Laryngology & …, 2023 - cambridge.org
ObjectivePost-tonsillectomy haemorrhage is an increasingly common cause of morbidity
following tonsillectomy. Secondary post-tonsillectomy haemorrhage occurring more than 24 …