Histone deacetylases (HDACs) catalyse removal of acetyl groups from lysine residues on
both histone and non‐histone proteins to control numerous cellular processes. Of the 11 …

Histone deacetylase (HDAC) 6 is the best‐characterized class II b deacetylase that
regulates many important biological processes via the formation of complexes with its …

Histone deacetylase (HDAC) 6 is a member of the class IIb HDAC family. This enzyme is
zinc-dependent and mainly localized in the cytoplasm. HDAC6 is a unique isoenzyme with …

Abstract Background HDAC9 (histone deacetylase 9) belongs to the class IIa family of
histone deacetylases. This enzyme can shuttle freely between the nucleus and cytoplasm …

Epigenetic regulation orchestrates many cellular processes and greatly influences key
disease mechanisms. Histone deacetylase (HDAC) enzymes play a crucial role either as …

Histone deacetylase 8 (HDAC8) is a class I HDAC that catalyzes the deacetylation of histone
and non-histone proteins. As one of the best-characterized isoforms, numerous studies have …

Histone deacetylases deacetylate histone and non-histone protein targets. Aberrant HDAC
expression and function have been observed in several diseases, which make these …

Histone deacetylases (HDACs) are a family of enzymes that remove acetyl groups on
histone and non-histone proteins, thereby playing a vital role in the modulation of gene …

The acetylation and deacetylation of histones plays an important role in the regulation of
gene transcriptions. Histone acetylation is mediated by histone acetyltransferase; the …

Abstract Histone deacetylase 4 (HDAC4) is a member of the HDACs family, its expression is
closely related to the cell development. The cell is an independent living entity that …