Sodium butyrate ameliorates Deoxynivalenol-induced oxidative stress and inflammation in the porcine liver via NR4A2-mediated histone acetylation

Q Zong, K Li, H Qu, P Hu, C Xu, H Wang… - Journal of Agricultural …, 2023 - ACS Publications
Mycotoxin-induced liver injury is often accompanied by oxidative stress (OS) and
inflammation. This research aimed to explore the potential mechanism of sodium butyrate …

[HTML][HTML] Dietary taurine supplementation counteracts deoxynivalenol-induced liver injury via alleviating oxidative stress, mitochondrial dysfunction, apoptosis, and …

X Ji, Z Tang, F Zhang, F Zhou, Y Wu, D Wu - … and Environmental Safety, 2023 - Elsevier
Deoxynivalenol (DON), as a widespread Fusarium mycotoxin in cereals, food products, and
animal feed, is detrimental to both human and animal health. The liver is not only the primary …

Sodium butyrate alleviates deoxynivalenol-induced hepatic cholesterol metabolic dysfunction via RORγ-mediated histone acetylation modification in weaning piglets

Q Zong, H Qu, Y Zhao, H Liu, S Wu, S Wang… - Journal of Animal …, 2022 - Springer
Background Cholesterol is an essential component of lipid rafts in cell plasma membrane,
which exerts a hepatoprotective role against mycotoxin exposure in pigs, and cholesterol …

Lactoferrin relieves Deoxynivalenol-induced oxidative stress and inflammatory response by modulating the Nrf2/MAPK pathways in the liver

P Hu, Y Liu, S Li, Y Zhao, H Gu, Q Zong… - Journal of Agricultural …, 2023 - ACS Publications
Deoxynivalenol (DON), one of the most common mycotoxins contaminating food and feed,
has been shown to induce hepatotoxicity. Lactoferrin (LF) enriched in human milk is a critical …

Baicalin alleviates deoxynivalenol-induced intestinal inflammation and oxidative stress damage by inhibiting NF-κB and increasing mTOR signaling pathways in …

P Liao, Y Li, M Li, X Chen, D Yuan, M Tang… - Food and Chemical …, 2020 - Elsevier
This study was conducted to evaluate the intestinal protective effects of baicalin (BAI) in
deoxynivalenol (DON)-treated piglets. A total of 320 weaned piglets were randomly allotted …

Deoxynivalenol exposure induces liver damage in mice: Inflammation and immune responses, oxidative stress, and protective effects of Lactobacillus rhamnosus GG

Y Bai, K Ma, J Li, J Li, C Bi, A Shan - Food and Chemical Toxicology, 2021 - Elsevier
Deoxynivalenol (DON), one of the most common environmental pollutants, substantially
affects human and animal health. Much attention has been paid to the ability of probiotics to …

Sodium butyrate protects against high-fat diet-induced oxidative stress in rat liver by promoting expression of nuclear factor E2-related factor 2

B Sun, Y Jia, S Yang, N Zhao, Y Hu, J Hong… - British Journal of …, 2019 - cambridge.org
Oxidative stress is closely related to metabolic disorders, which can lead to various
diseases. Nuclear factor E2-related factor 2 (Nrf2) is a central regulator of oxidative stress …

[HTML][HTML] Curcumin protects against Aflatoxin B1-induced liver injury in broilers via the modulation of long non-coding RNA expression

S Li, R Liu, G Wei, G Guo, H Yu, Y Zhang… - Ecotoxicology and …, 2021 - Elsevier
Abstract Aflatoxin B1 (AFB1) is a potent hepatotoxic and carcinogenic agent. Curcumin
possesses potential anti-inflammatory, anti-oxidative and hepatoprotective effects. However …

Sodium butyrate alleviates deoxynivalenol-induced porcine intestinal barrier disruption by promoting mitochondrial homeostasis via PCK2 signaling

D Xue, Y Cheng, T Pang, Y Kuai, Y An, K Wu… - Journal of hazardous …, 2023 - Elsevier
Deoxynivalenol (DON) is one of the most plentiful trichothecenes occurring in food and feed,
which brings severe health hazards to both animals and humans. This study aims to …

Sodium butyrate protects the intestinal barrier by modulating intestinal host defense peptide expression and gut microbiota after a challenge with deoxynivalenol in …

S Wang, C Zhang, J Yang, X Wang, K Wu… - Journal of agricultural …, 2020 - ACS Publications
This study aims to determine whether sodium butyrate (SB) could antagonize
deoxynivalenol (DON)-induced intestinal epithelial dysfunction. In a four-week feeding trial …