Polycaprolactone/epoxide-functionalized silica composite microparticles for long-term controlled release of trans-chalcone

Y Kaptan, Y Güvenilir - Journal of Polymer Engineering, 2023 - degruyter.com
In this study, controlled release of trans-chalcone was achieved by using a polycaprolactone-
based hybrid system as the drug carrier material. Encapsulation efficiency was obtained in …

Enzymatic PCL-grafting to NH2-end grouped silica and development of microspheres for pH-stimulated release of a hydrophobic model drug

Y Kaptan, Y Güvenilir - European Journal of Pharmaceutics and …, 2022 - Elsevier
This study set out to evaluate novel PCL-based silica containing nanohybrids as the polymer
matrix in a hydrophobic drug-loaded microsphere system. Nanohybrids were synthesized by …

Drug release optimization from microparticles of poly (E-caprolactone) and hydroxypropyl methylcellulose polymeric blends: formulation and characterization

I Javed, NM Ranjha, K Mahmood, S Kashif… - Journal of Drug Delivery …, 2014 - Elsevier
In this study, polymeric blend microparticles are prepared with tunable drug releasing
behavior, imparted by using poly (e-caprolactone)(PCL) as hydrophobic and hydroxypropyl …

Microencapsulation of fluticasone propionate and salmeterol xinafoate in modified chitosan microparticles for release optimization

NM Ainali, E Xanthopoulou, G Michailidou… - Molecules, 2020 - mdpi.com
Chitosan (CS) is a natural polysaccharide, widely studied in the past due to its unique
properties such as biocompatibility, biodegradability and non-toxicity. Chemical modification …

[PDF][PDF] Biodegradable micro and nanoparticles for controlled drug release

C Mattu, S Sartori, E Ranzato, M Boffito, R Li… - … , MEMS, Fluidics and …, 2011 - academia.edu
In this paper, we propose the encapsulation of the anticancer drug Paclitaxel into
biodegrdable polymeric carriers to improve the release properties of the active principle …

Fabrication and characterization of dual drug-loaded poly (lactic-co-glycolic acid) fiber-microsphere composite scaffolds

W Zhao, W Liu, R Xu, Y Wang, K Jin… - International Journal of …, 2019 - Taylor & Francis
The purpose of this work is to develop dual drug-loaded poly (lactic-co-glycolic acid)(PLGA)
fiber-microsphere composite scaffolds with desired morphologies and dual drug loading …

[PDF][PDF] Development of novel controlled release gliclazide-loaded poly (ε-caprolactone) microparticles: effect of polymer blends

NS Barakat, G Al-Shazli, AH Almedany - Pharm Anal Acta, 2012 - academia.edu
Gliclazide-loaded microparticles made with a polymeric blend were prepared by a solvent
evaporation technique. Organic solutions of two polymers, poly (epsilon-caprolactone)(PCL) …

Biodegradable paclitaxel‐loaded microparticles prepared from novel block copolymers: influence of polymer composition on drug encapsulation and release

S Sartori, A Caporale, A Rechichi… - Journal of Peptide …, 2013 - Wiley Online Library
This study covers the preparation of microspheres for the controlled and targeted release of
paclitaxel, using novel degradable polymers as carrier materials. Paclitaxel‐loaded …

Drug distribution within poly (ɛ-caprolactone) microspheres and in vitro release

X Wang, Y Wang, K Wei, N Zhao, S Zhang… - Journal of Materials …, 2009 - Elsevier
Poly (ɛ-caprolactone)(PCL) microspheres loaded two model compounds (p-nitroaniline and
rhodamine B) with different water solubilities were prepared by an s/o/w single emulsion …

Effects of crystalline microstructure on drug release behavior of poly (ε-caprolactone) microspheres

JC Jeong, J Lee, K Cho - Journal of controlled release, 2003 - Elsevier
This study investigates the release behavior of papaverine from poly (ε-caprolactone)(PCL)
microparticles prepared by the oil/water solvent evaporation method. Microparticles were …