In utero, the developing brain is highly susceptible to the environment. For example, adverse
maternal experiences during the prenatal period are associated with outcomes such as …

Variations in serotoninergic signaling have been related to behavioral outcomes. Alterations
in the genome, such as DNA methylation and histone modifications, are affected by …

Importance Prenatal maternal psychological distress is associated with disturbances in fetal
brain development. However, the association between altered fetal brain development …

Importance Exposure to early life adversity alters the structural development of key brain
regions underlying neurodevelopmental impairments. The extent that prenatal exposure to …

Background Maternal distress is associated with an increased risk for adverse emotional
development in infants, including difficulties with emotion regulation. Prenatal maternal …

Prenatal adversity has been linked to later psychopathology. Yet, research on cumulative
prenatal adversity, as well as its interaction with offspring genotype, on brain and behavioral …

Prenatal maternal stress is highly prevalent and predicts many child psychopathologies.
Here, we apply the fetal programming hypothesis as an organizational framework to address …

The prenatal period is increasingly considered as a crucial target for the primary prevention
of neurodevelopmental and psychiatric disorders. Understanding their pathophysiological …

Inflammatory signaling has a role in sensing intrauterine environment, which may be
moderators in altering fetal brain development upon maternal environment. This study …

Maternal exposure to stress during pregnancy is associated with increased risk for cognitive
and behavioral sequelae in offspring. Animal research demonstrates exposure to stress …