[HTML][HTML] Establishing normative data for the evaluation of cognitive performance in Huntington's disease considering the impact of gender, age, language, and …

A Mühlbäck, J Mana, M Wallner, W Frank… - Journal of …, 2023 - Springer
Background A declining cognitive performance is a hallmark of Huntington's disease (HD).
The neuropsychological battery of the Unified HD Rating Scale (UHDRS'99) is commonly …

Agreement between clinician-rated versus patient-reported outcomes in Huntington disease

NE Carlozzi, NR Boileau, JS Perlmutter, KL Chou… - Journal of …, 2018 - Springer
Background Clinician-rated measures of functioning are often used as primary endpoints in
clinical trials and other behavioral research in Huntington disease. As study costs for …

[HTML][HTML] Measuring cognitive impairment and monitoring cognitive decline in Huntington's disease: a comparison of assessment instruments

A Horta-Barba, S Martinez-Horta, J Pérez-Pérez… - Journal of …, 2023 - Springer
Background Progressive cognitive decline is an inevitable feature of Huntington's disease
(HD) but specific criteria and instruments are still insufficiently developed to reliably classify …

Validation Study of a German Cognitive Battery for Huntington's Disease: Relationship Between Cognitive Performance, Functional Decline, and Disease Burden

A Mühlbäck, W Frank, O Klempířová… - Archives of Clinical …, 2021 - academic.oup.com
Objective Cognitive decline is a key characteristic of Huntington's disease (HD). This study
aimed to investigate the diagnostic accuracy of a cognitive battery with six tests used by …

Cognitive deficits predict poorer functional capacity in Huntington's disease: But what is being measured?

CM Eddy, HE Rickards - Neuropsychology, 2015 - psycnet.apa.org
Objective: Huntington's disease (HD) is an inherited movement disorder characterized by
choreiform movements and frontostriatal dysfunction. Previous studies have documented …

[HTML][HTML] Comparison of cognitive and UHDRS measures in monitoring disease progression in Huntington's disease: a 12-month longitudinal study

EA Toh, MR MacAskill, JC Dalrymple-Alford… - Translational …, 2014 - Springer
Progressive cognitive decline is a feature of Huntington's disease (HD), an inherited
neurodegenerative movement disorder. Comprehensive neuropsychological testing is the …

Psychometric properties and responsiveness of Neuro-QoL Cognitive Function in persons with Huntington disease (HD)

NE Carlozzi, NR Boileau, JS Paulsen… - Quality of Life …, 2020 - Springer
Abstract Purpose Individuals with Huntington disease (HD) experience progressive
cognitive decline that may appear years before motor manifestations of the disease. These …

Understanding patient-reported outcome measures in Huntington disease: at what point is cognitive impairment related to poor measurement reliability?

NE Carlozzi, S Schilling, AL Kratz, JS Paulsen… - Quality of Life …, 2018 - Springer
Abstract Purpose Symptom progression in Huntington disease (HD) is associated with
cognitive decline which may interfere with the self-report of symptoms. Unfortunately, data to …

Controlling for Individual Differences in Neurocognitive Markers in Pre-Diagnosis HD in the PREDICT-HD Cohort

JC Stout, S Queller, KB Whitlock… - …, 2008 - neurotherapeuticsjournal.org
Background Prior to clinical diagnosis, individuals with the CAG expansion for Huntington's
disease demonstrate subtle impairment on a number of neurocognitive tests relative to …

[HTML][HTML] Measuring the functional impact of cognitive impairment in Huntington's disease

A Horta-Barba, S Martínez-Horta, J Pérez-Pérez… - Journal of …, 2022 - Springer
Abstract Background Patients with Huntington's disease (HD) exhibit a variable
predominance of cognitive, behavioral and motor symptoms. A specific instrument focusing …