Females are more likely than males to develop post-traumatic stress disorder (PTSD).
However, the neurobiological mechanisms responsible for these sex differences remain …

Ubiquitin-proteasome mediated protein degradation has been widely implicated in fear
memory formation in the amygdala. However, to date, the protein targets of the proteasome …

Background Sex differences have been observed in several brain regions for the molecular
mechanisms involved in baseline (resting) and memory-related processes. The ubiquitin …

Strong evidence supports that protein ubiquitination is a critical regulator of fear memory
formation. However, as this work has focused on protein degradation, it is currently unknown …

Over the last decade, strong evidence has emerged that protein degradation mediated by
the ubiquitin-proteasome system is critical for fear memory formation in the amygdala …

Protein degradation through the ubiquitin-proteasome system [UPS] plays a critical role in
some forms of synaptic plasticity. However, its role in memory formation in the amygdala, a …

Brain aging is accompanied by an accumulation of damaged proteins, which results from
deterioration of cellular quality control mechanisms and decreased protein degradation. The …

Numerous studies have supported a critical role for the ubiquitin-proteasome system (UPS)
in the memory consolidation and reconsolidation processes. The protein targets and …

The ubiquitin proteasome system (UPS) is a primary mechanism through which proteins are
degraded in cells. UPS activity in the dorsal hippocampus (DH) is necessary for multiple …

Strong evidence has implicated proteasome-mediated protein degradation in the memory
consolidation process. However, due to the use of pharmacological approaches, the cell …