Unfavourable developmental environments are believed to" program" offspring to metabolic
disease. In this thesis, the effects of dietary programming on telomere length were examined …

A substantial body of evidence suggests that suboptimal conditions in intrauterine and early
postnatal life play a critical role in subsequent health and susceptibility for a range of …

Optimal nutritional supply to the developing fetus is paramount to achieving appropriate fetal
growth and development. Nutrition prior to1, 2 and during early pregnancy3, 4 may impact …

Adverse prenatal environmental conditions, including stress, infections, and obesity, are
known to be developmental risk factors for certain diseases in later life. This chapter …

Rationale/statement of the problem: Substantial evidence suggests conditions in intrauterine
life may play a critical role in subsequent health and disease susceptibility related outcomes …

Background Telomere length at birth is a major determinant of telomere length in late
adulthood. However, the prenatal setting of telomere length is poorly understood. Individuals …

Research on mechanisms underlying fetal programming of health and disease risk has
focused primarily on processes that are specific to cell types, organs or phenotypes of …

Advances in epigenetics now enable us to better understand environmental influences on
the genetic background of human diseases. This refers especially to fetal development …

Aging is a complex physiological process responsive to the genetic background and
environmental factors operative during the life course of an individual. Attrition of telomeres …

We sought to synthesize a comprehensive literature review comprising recent research
linking fetal programming to fetal telomere length. We also explored the potential effects fetal …