Treatment with Ligilactobacillus murinus lowers blood pressure and intestinal permeability in spontaneously hypertensive rats
M Mukohda, T Yano, T Matsui, S Nakamura… - Scientific Reports, 2023 - nature.com
One feature of hypertension is a microbial imbalance with increased intestinal permeability.
In this study, we examined whether an alteration in the microbiota affects blood pressure …
In this study, we examined whether an alteration in the microbiota affects blood pressure …
Transcriptomic signature of gut microbiome-contacting cells in colon of spontaneously hypertensive rats
Fecal matter transfer from hypertensive patients and animals into normotensive animals
increases blood pressure, strengthening the evidence for gut-microbiota interactions in the …
increases blood pressure, strengthening the evidence for gut-microbiota interactions in the …
Gut microbiota dysbiosis contributes to the development of hypertension
Background Recently, the potential role of gut microbiome in metabolic diseases has been
revealed, especially in cardiovascular diseases. Hypertension is one of the most prevalent …
revealed, especially in cardiovascular diseases. Hypertension is one of the most prevalent …
Genetically determined hypertensive phenotype affects gut microbiota composition, but not vice versa
P Konopelski, M Konop, K Perlejewski… - Journal of …, 2021 - journals.lww.com
Objectives: Research suggests reciprocal crosstalk between the host and gut bacteria. This
study evaluated the interaction between gut microbiota and arterial blood pressure (BP) in …
study evaluated the interaction between gut microbiota and arterial blood pressure (BP) in …
Alterations in the gut microbiota can elicit hypertension in rats
S Adnan, JW Nelson, NJ Ajami… - Physiological …, 2017 - journals.physiology.org
Gut dysbiosis has been linked to cardiovascular diseases including hypertension. We tested
the hypothesis that hypertension could be induced in a normotensive strain of rats or …
the hypothesis that hypertension could be induced in a normotensive strain of rats or …
Imbalance of gut microbiome and intestinal epithelial barrier dysfunction in patients with high blood pressure
Recent evidence indicates a link between gut pathology and microbiome with hypertension
(HTN) in animal models. However, whether this association exists in humans is unknown …
(HTN) in animal models. However, whether this association exists in humans is unknown …
Intestinal microbiota: A promising therapeutic target for hypertension
D Sun, H Xiang, J Yan, L He - Frontiers in Cardiovascular Medicine, 2022 - frontiersin.org
Hypertension has developed into an escalating serious global public health problem with
multiple and unclear pathophysiological mechanisms. Recent studies have identified …
multiple and unclear pathophysiological mechanisms. Recent studies have identified …
Microbiota under pressure
A Aguilar - Nature Reviews Nephrology, 2017 - nature.com
Dysbiosis of the gut microbiota is involved in severe conditions such as chronic kidney
disease but whether the gut–microbiome link is altered in hypertension has not been …
disease but whether the gut–microbiome link is altered in hypertension has not been …
The role and mechanism of intestinal flora in blood pressure regulation and hypertension development
J Li, X Yang, X Zhou, J Cai - Antioxidants & Redox Signaling, 2021 - liebertpub.com
Significance: Hypertension (HTN) has a complex etiology that is characterized by genetic
and environmental factors. It has become a global health burden leading to cardiovascular …
and environmental factors. It has become a global health burden leading to cardiovascular …
Microbiota introduced to germ-free rats restores vascular contractility and blood pressure
Commensal gut microbiota are strongly correlated with host hemodynamic homeostasis but
only broadly associated with cardiovascular health. This includes a general correspondence …
only broadly associated with cardiovascular health. This includes a general correspondence …