Background: Leukocyte progenitors derived from clonal hematopoiesis of undetermined
potential (CHIP) are associated with increased cardiovascular events. However, the …

BACKGROUND: Clonal hematopoiesis of indeterminate potential (CHIP) occurs due to
acquired mutations in bone marrow progenitor cells. CHIP confers a 2-fold risk of …

Individuals with clonal hematopoiesis of indeterminate potential (CHIP) is associated with a
2-4 fold increase in cardiovascular diseases (CVDs). While most studies focus on mutant …

Hematopoiesis is the process of blood production, essential for the continued supply of
immune cells and red blood cells. However, the proliferative nature of hematopoietic stem …

Clonal hematopoiesis of indeterminate potential (CHIP) occurs as a result of acquired
mutations in bone marrow progenitor cells. CHIP confers a twofold risk of atherosclerotic …

Clonal haematopoiesis of indeterminate potential (CHIP) is defined as an expansion of
mutant blood stem cells in individuals without haematological malignancies. CHIP is linked …

Background Clonal hematopoiesis of indeterminate potential (CHIP)—the age-related clonal
expansion of blood stem cells with leukemia-associated mutations—is a novel …

With age, acquired mutations can cause clonal expansion of hematopoietic stem cells
(HSC). This clonal hematopoiesis of indeterminate potential (CHIP) leads to an increased …

Circulation. 2018; 138: 666–668. DOI: 10.1161/CIRCULATIONAHA. 118.034392 August 14,
2018 667 factors, CHIP carriers have almost a doubling in the relative risk of cardiovascular …

Background: Clonal hematopoiesis of indeterminate potential (CHIP) occurs when
hematopoietic stem cells acquire mutations that confer a proliferative advantage. CHIP is …