[HTML][HTML] Cannabidiol-loaded nanocarriers and their therapeutic applications
Cannabidiol (CBD), one of the most promising constituents isolated from Cannabis sativa,
exhibits diverse pharmacological actions. However, the applications of CBD are restricted …
exhibits diverse pharmacological actions. However, the applications of CBD are restricted …
[HTML][HTML] Promising nanocarriers to enhance solubility and bioavailability of cannabidiol for a plethora of therapeutic opportunities
In recent years, the interest in cannabidiol (CBD) has increased because of the lack of
psychoactive properties. However, CBD has low solubility and bioavailability, variable …
psychoactive properties. However, CBD has low solubility and bioavailability, variable …
Current trends on cannabidiol delivery systems: where are we and where are we going?
ÍMM Ramalho, DT Pereira, GBL Galvão… - Expert Opinion on …, 2021 - Taylor & Francis
Introduction Cannabidiol (CBD), a phytocannabinoid from Cannabis sativa, has several
therapeutic properties. However, its high lipophilicity, metabolization, and instability impair …
therapeutic properties. However, its high lipophilicity, metabolization, and instability impair …
[HTML][HTML] Current Challenges and Opportunities for Improved Cannabidiol Solubility
Cannabidiol (CBD), derived from the cannabis plant, has gained significant attention due to
its potential therapeutic benefits. However, one of the challenges associated with CBD …
its potential therapeutic benefits. However, one of the challenges associated with CBD …
Nanoformulations as a strategy to overcome the delivery limitations of cannabinoids
Medical cannabis has received significant interest in recent years due to its promising
benefits in the management of pain, anxiety, depression and neurological and movement …
benefits in the management of pain, anxiety, depression and neurological and movement …
[HTML][HTML] Towards better delivery of cannabidiol (CBD)
SA Millar, RF Maguire, AS Yates, SE O'Sullivan - Pharmaceuticals, 2020 - mdpi.com
Cannabidiol (CBD) has substantial therapeutic potential, but its development as an effective
drug by the pharmaceutical industry is hindered by intrinsic characteristics such as low …
drug by the pharmaceutical industry is hindered by intrinsic characteristics such as low …
Enhanced Intramuscular Bioavailability of Cannabidiol Using Nanocrystals: Formulation, In Vitro Appraisal, and Pharmacokinetics
X Fu, S Xu, Z Li, K Chen, H Fan, Y Wang, Z Xie… - AAPS …, 2022 - Springer
Cannabidiol (CBD) has poor water solubility and is subjected to extensive first-pass
metabolism. These absorption obstacles are responsible for low and variable oral …
metabolism. These absorption obstacles are responsible for low and variable oral …
Poly(ethylene glycol)-b-poly(epsilon-caprolactone) nanoparticles as a platform for the improved oral delivery of cannabidiol
I Shreiber-Livne, L Sulimani, A Shapira… - Drug Delivery and …, 2023 - Springer
Abstract Cannabidiol (CBD), a non-psychoactive constituent of Cannabis, has proven
neuroprotective, anti-inflammatory and antioxidant properties though his therapeutic use …
neuroprotective, anti-inflammatory and antioxidant properties though his therapeutic use …
Lipid-based formulations to increase cannabidiol bioavailability: In vitro digestion tests, pre-clinical assessment and clinical trial
MAA De Prá, R Vardanega, CG Loss - International Journal of …, 2021 - Elsevier
Herein, medium-chain triglycerides (MCT), glyceryl monolinoleate (GML), and a self-
emulsifying drug delivery system (SEDDS) for cannabidiol (CBD) delivery were compared …
emulsifying drug delivery system (SEDDS) for cannabidiol (CBD) delivery were compared …
[HTML][HTML] Development and pharmacokinetic evaluation of a self-nanoemulsifying drug delivery system for the oral delivery of cannabidiol
LY Kok, P Bannigan, F Sanaee, JC Evans… - European Journal of …, 2022 - Elsevier
The number of lipophilic drug candidates in pharmaceutical discovery pipelines has
increased in recent years. These drugs often possess physicochemical properties that result …
increased in recent years. These drugs often possess physicochemical properties that result …