Water-soluble copper (II) 5-fluorouracil complexes bearing polypyridyl co-ligands: synthesis, structures and anticancer activity

C Icsel, VT Yilmaz, M Aygun, M Erkisa… - Dalton Transactions, 2023 - pubs.rsc.org
Five newly synthesized copper (II) 5-fluorouracil (5-FU) complexes of polypyridyl co-ligands
with good solubility in water, namely [CuCl (5-FU)(bpy)(DMSO)](1),[Cu (5-FU)(phen) 2](5 …

Fluorophore tagged mixed ligand copper (II) complexes: synthesis, structural characterization, protein binding, DNA cleavage and anticancer activity

SA Shaikh, SS Bhat, VK Revankar, BD Kulkarni… - …, 2021 - Wiley Online Library
Two fluorophore tagged copper (II) complexes [Cu (phen)(L)(ClO4) 2](1) and [Cu
(bpy)(L)(H2O)(ClO4)](ClO4)(2),(where L= 2‐amino‐1H‐benzo [de] isoquinoline‐1, 3‐(2H) …

Two new Cu (II) complexes based on 5‐fluorouracil‐1‐yl acetic acid and N‐donor ligands: Investigation of their interaction with DNA and anticancer activity

YH Xi, X Yan, F Bigdeli, Q Zhang… - Applied …, 2022 - Wiley Online Library
Two new Cu (II) complexes [Cu (bpy) 2L1] BF4. CH3OH (Z3) and [Cu (phen) 2L1] BF4· H2O
(Z9), L1= 5‐Fluorouracil‐1‐yl Acetic Acid, were synthesized based on 5‐Fluorouracil‐1‐yl …

Water-soluble copper (II) complexes with 4, 5-dichloro-isothiazole-3-carboxylic acid and heterocyclic N-donor ligands: Synthesis, crystal structures, cytotoxicity, and …

JA Eremina, EV Lider, TS Sukhikh, LS Klyushova… - Inorganica Chimica …, 2020 - Elsevier
Mixed-ligand copper (II) complexes based on 1, 10-phenanthroline and related compounds
are of interest to scientists due to their promising anticancer properties. In this study, four …

Mixed ligand copper (II) dicarboxylate complexes: the role of co-ligand hydrophobicity in DNA binding, double-strand DNA cleavage, protein binding and cytotoxicity

R Loganathan, S Ramakrishnan… - Dalton …, 2015 - pubs.rsc.org
A few water soluble mixed ligand copper (II) complexes of the type [Cu (bimda)(diimine)] 1–
5, where bimda is N-benzyliminodiacetic acid and diimine is 2, 2′-bipyridine (bpy, 1) or 1 …

Copper (II) complexes possessing alkyl-substituted polypyridyl ligands: structural characterization and in vitro antitumor activity

NR Angel, RM Khatib, J Jenkins, M Smith… - Journal of Inorganic …, 2017 - Elsevier
In an effort to find alternatives to the antitumor drug cisplatin, a series of copper (II)
complexes possessing alkyl-substituted polypyridyl ligands have been synthesized. Eight …

Functional copper complexes with benzofurans tridentate ligand: Synthesis, crystal structure, DNA binding and anticancer studies

YM Chen, YC Liu, JQ Wang, GC Ou, XF Wang… - Journal of Inorganic …, 2023 - Elsevier
Metal complexes, particularly copper (II) complexes, are often used as anticancer drugs due
to their ability to generate reactive oxygen species (ROS) in cells. Four copper (II) complexes …

[HTML][HTML] Novel Copper (II) Complexes with Fluorine-Containing Reduced Schiff Base Ligands Showing Marked Cytotoxicity in the HepG2 Cancer Cell Line

B Oboňová, J Valentová, M Litecká, Ľ Pašková… - International Journal of …, 2024 - mdpi.com
Several novel copper (II) complexes of reduced Schiff bases containing fluoride substituents
were prepared and structurally characterized by single-crystal X-ray diffraction. The …

Highly cytotoxic copper (II) terpyridine complexes as anticancer drug candidates

J Karges, K Xiong, O Blacque, H Chao… - Inorganica Chimica Acta, 2021 - Elsevier
Cancer is one of the deadliest diseases worldwide. Chemotherapy remains one of the
frequently applied treatment modalities in the clinics. However, as the currently applied …

Mononuclear Copper (II) Complexes with Polypyridyl Ligands: Synthesis, Characterization, DNA Interactions/Cleavages and in vitro Cytotoxicity towards Human …

A Muley, S Kumbhakar, R Raut, S Mathur, I Roy… - Dalton …, 2024 - pubs.rsc.org
DNA being the necessary element in cell regeneration, an approach to combat cancer cells
is the controlled cellular apoptosis by DNA binding/cleaving. The widely prescribed …