Water-soluble copper (II) 5-fluorouracil complexes bearing polypyridyl co-ligands: synthesis, structures and anticancer activity
Five newly synthesized copper (II) 5-fluorouracil (5-FU) complexes of polypyridyl co-ligands
with good solubility in water, namely [CuCl (5-FU)(bpy)(DMSO)](1),[Cu (5-FU)(phen) 2](5 …
with good solubility in water, namely [CuCl (5-FU)(bpy)(DMSO)](1),[Cu (5-FU)(phen) 2](5 …
Fluorophore tagged mixed ligand copper (II) complexes: synthesis, structural characterization, protein binding, DNA cleavage and anticancer activity
Two fluorophore tagged copper (II) complexes [Cu (phen)(L)(ClO4) 2](1) and [Cu
(bpy)(L)(H2O)(ClO4)](ClO4)(2),(where L= 2‐amino‐1H‐benzo [de] isoquinoline‐1, 3‐(2H) …
(bpy)(L)(H2O)(ClO4)](ClO4)(2),(where L= 2‐amino‐1H‐benzo [de] isoquinoline‐1, 3‐(2H) …
Two new Cu (II) complexes based on 5‐fluorouracil‐1‐yl acetic acid and N‐donor ligands: Investigation of their interaction with DNA and anticancer activity
YH Xi, X Yan, F Bigdeli, Q Zhang… - Applied …, 2022 - Wiley Online Library
Two new Cu (II) complexes [Cu (bpy) 2L1] BF4. CH3OH (Z3) and [Cu (phen) 2L1] BF4· H2O
(Z9), L1= 5‐Fluorouracil‐1‐yl Acetic Acid, were synthesized based on 5‐Fluorouracil‐1‐yl …
(Z9), L1= 5‐Fluorouracil‐1‐yl Acetic Acid, were synthesized based on 5‐Fluorouracil‐1‐yl …
Water-soluble copper (II) complexes with 4, 5-dichloro-isothiazole-3-carboxylic acid and heterocyclic N-donor ligands: Synthesis, crystal structures, cytotoxicity, and …
JA Eremina, EV Lider, TS Sukhikh, LS Klyushova… - Inorganica Chimica …, 2020 - Elsevier
Mixed-ligand copper (II) complexes based on 1, 10-phenanthroline and related compounds
are of interest to scientists due to their promising anticancer properties. In this study, four …
are of interest to scientists due to their promising anticancer properties. In this study, four …
Mixed ligand copper (II) dicarboxylate complexes: the role of co-ligand hydrophobicity in DNA binding, double-strand DNA cleavage, protein binding and cytotoxicity
R Loganathan, S Ramakrishnan… - Dalton …, 2015 - pubs.rsc.org
A few water soluble mixed ligand copper (II) complexes of the type [Cu (bimda)(diimine)] 1–
5, where bimda is N-benzyliminodiacetic acid and diimine is 2, 2′-bipyridine (bpy, 1) or 1 …
5, where bimda is N-benzyliminodiacetic acid and diimine is 2, 2′-bipyridine (bpy, 1) or 1 …
Copper (II) complexes possessing alkyl-substituted polypyridyl ligands: structural characterization and in vitro antitumor activity
NR Angel, RM Khatib, J Jenkins, M Smith… - Journal of Inorganic …, 2017 - Elsevier
In an effort to find alternatives to the antitumor drug cisplatin, a series of copper (II)
complexes possessing alkyl-substituted polypyridyl ligands have been synthesized. Eight …
complexes possessing alkyl-substituted polypyridyl ligands have been synthesized. Eight …
Functional copper complexes with benzofurans tridentate ligand: Synthesis, crystal structure, DNA binding and anticancer studies
YM Chen, YC Liu, JQ Wang, GC Ou, XF Wang… - Journal of Inorganic …, 2023 - Elsevier
Metal complexes, particularly copper (II) complexes, are often used as anticancer drugs due
to their ability to generate reactive oxygen species (ROS) in cells. Four copper (II) complexes …
to their ability to generate reactive oxygen species (ROS) in cells. Four copper (II) complexes …
[HTML][HTML] Novel Copper (II) Complexes with Fluorine-Containing Reduced Schiff Base Ligands Showing Marked Cytotoxicity in the HepG2 Cancer Cell Line
B Oboňová, J Valentová, M Litecká, Ľ Pašková… - International Journal of …, 2024 - mdpi.com
Several novel copper (II) complexes of reduced Schiff bases containing fluoride substituents
were prepared and structurally characterized by single-crystal X-ray diffraction. The …
were prepared and structurally characterized by single-crystal X-ray diffraction. The …
Highly cytotoxic copper (II) terpyridine complexes as anticancer drug candidates
Cancer is one of the deadliest diseases worldwide. Chemotherapy remains one of the
frequently applied treatment modalities in the clinics. However, as the currently applied …
frequently applied treatment modalities in the clinics. However, as the currently applied …
Mononuclear Copper (II) Complexes with Polypyridyl Ligands: Synthesis, Characterization, DNA Interactions/Cleavages and in vitro Cytotoxicity towards Human …
DNA being the necessary element in cell regeneration, an approach to combat cancer cells
is the controlled cellular apoptosis by DNA binding/cleaving. The widely prescribed …
is the controlled cellular apoptosis by DNA binding/cleaving. The widely prescribed …
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- dna cleavage ligand copper
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- crystal structure copper complexes
- dicarboxylate complexes ligand copper
- mononuclear copper polypyridyl ligands
- complexes with phenanthroline cytotoxic copper
- complexes with phenanthroline mixed ligands
- cytotoxic copper mixed ligands
- dna interactions polypyridyl ligands
- anticancer activity dna cleavage
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- anticancer activity acetic acid
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