Neurological adverse events of immune checkpoint inhibitors: an update of clinical presentations, diagnosis, and management

A Farina, M Villagrán-García, J Honnorat - Revue Neurologique, 2023 - Elsevier
The use of immune checkpoint inhibitors (ICIs) has represented a major advance in cancer
treatment. By enhancing endogenous immune responses to destroy cancer cells, ICIs can …

Neurological immune‐related adverse events associated with immune checkpoint inhibitors: A review of the literature

S Fan, H Ren, L Zhao, J Yin, G Feng… - Asia‐Pacific Journal …, 2020 - Wiley Online Library
Immune checkpoint inhibitors (ICIs) have made a breakthrough in cancer therapy. Patients
treated with ICIs may develop immune‐related adverse events (irAEs) due to the …

Neurologic immune-related adverse events associated with immune checkpoint inhibition

PC Pan, A Haggiagi - Current Oncology Reports, 2019 - Springer
Abstract Purpose of Review This review highlights the spectrum of neurologic adverse
events seen with use of immune checkpoint inhibitors (ICIs), their potential mechanisms, the …

CNS and PNS manifestation in immune checkpoint inhibitors: a systematic review

E Khan, AK Shrestha, M Elkhooly, H Wilson… - Journal of the …, 2022 - Elsevier
Introduction Immunomodulatory therapies, including the use of immune checkpoint inhibitors
(ICIs), have made a profound impact on treatment of advanced cancers in recent decades …

Neurological adverse events associated with immune checkpoint inhibitors: diagnosis and management

C Astaras, R de Micheli, B Moura… - Current Neurology and …, 2018 - Springer
Abstract Purpose of Review Immune checkpoint inhibitors represent a major step forward in
the field of oncologic immunotherapy these last years and have significantly increased …

Severe neurologic complications of immune checkpoint inhibitors: a single-center review

S Mancone, T Lycan, T Ahmed, U Topaloglu… - Journal of …, 2018 - Springer
Abstract Background Immune checkpoint inhibitors (ICIs) are a promising class of anticancer
drugs associated with immune-related adverse events (IRAEs). In registration studies of …

Neurotoxicity and safety of the rechallenge of immune checkpoint inhibitors: a growing issue in neuro-oncology practice

M Villagrán-García, R Velasco - Neurological Sciences, 2022 - Springer
Neurological, immune-related adverse events (n-irAE) due to immune checkpoint inhibitors
(ICI) represent a growing clinical problem in neuro-oncology practice. Although rare, the …

How to diagnose and manage neurological toxicities of immune checkpoint inhibitors: an update

A Vogrig, S Muñiz-Castrillo, A Farina, J Honnorat… - Journal of …, 2022 - Springer
As the use of cancer immunotherapy with immune checkpoint inhibitors (ICIs) is expanding
rapidly for the treatment of many tumor types, it is crucial that both neurologists and …

Neurologic complications of immune checkpoint inhibitors

AM Haugh, JC Probasco… - Expert opinion on drug …, 2020 - Taylor & Francis
Introduction: Immune checkpoint inhibitors (ICI) are associated with a wide spectrum of
neurologic immune-related adverse events (irAEs) including meningo-encephalitis …

Immune-related adverse events and immune checkpoint inhibitors: a focus on neurotoxicity and clinical management

R Ruggiero, R Di Napoli, N Balzano… - Expert Review of …, 2023 - Taylor & Francis
ABSTRACT Introduction Immune checkpoint inhibitors (ICIs) represent an innovative
therapeutic approach of oncologic diseases. In Europe, this therapeutic class currently …