[HTML][HTML] Transposable elements as essential elements in the control of gene expression

A Gebrie - Mobile DNA, 2023 - Springer
Interspersed repetitions called transposable elements (TEs), commonly referred to as mobile
elements, make up a significant portion of the genomes of higher animals. TEs contribute in …

[HTML][HTML] Role of transposable elements in gene regulation in the human genome

A Ali, K Han, P Liang - Life, 2021 - mdpi.com
Transposable elements (TEs), also known as mobile elements (MEs), are interspersed
repeats that constitute a major fraction of the genomes of higher organisms. As one of their …

Transposable elements as a potent source of diverse cis-regulatory sequences in mammalian genomes

V Sundaram, J Wysocka - Philosophical Transactions of …, 2020 - royalsocietypublishing.org
Eukaryotic gene regulation is mediated by cis-regulatory elements, which are embedded
within the vast non-coding genomic space and recognized by the transcription factors in a …

Retrotransposons as regulators of gene expression

RA Elbarbary, BA Lucas, LE Maquat - Science, 2016 - science.org
BACKGROUND Genomes are subject to two types of changes: changes to the DNA
sequence, and changes that are epigenetic in nature. Changes to the DNA sequence can …

[HTML][HTML] Transposable elements generate regulatory novelty in a tissue-specific fashion

M Trizzino, A Kapusta, CD Brown - BMC genomics, 2018 - Springer
Background Transposable elements (TE) are an important source of evolutionary novelty in
gene regulation. However, the mechanisms by which TEs contribute to gene expression are …

[HTML][HTML] Tissue-specific usage of transposable element-derived promoters in mouse development

B Miao, S Fu, C Lyu, P Gontarz, T Wang, B Zhang - Genome biology, 2020 - Springer
Abstract Background Transposable elements (TEs) are a significant component of
eukaryotic genomes and play essential roles in genome evolution. Mounting evidence …

Roles of transposable elements in the regulation of mammalian transcription

R Fueyo, J Judd, C Feschotte, J Wysocka - Nature reviews Molecular …, 2022 - nature.com
Transposable elements (TEs) comprise about half of the mammalian genome. TEs often
contain sequences capable of recruiting the host transcription machinery, which they use to …

TranspoGene and microTranspoGene: transposed elements influence on the transcriptome of seven vertebrates and invertebrates

A Levy, N Sela, G Ast - Nucleic acids research, 2008 - academic.oup.com
Transposed elements (TEs) are mobile genetic sequences. During the evolution of
eukaryotes TEs were inserted into active protein-coding genes, affecting gene structure …

Origin of a substantial fraction of human regulatory sequences from transposable elements

IK Jordan, IB Rogozin, GV Glazko, EV Koonin - TRENDS in Genetics, 2003 - cell.com
Transposable elements (TEs) are abundant in mammalian genomes and have potentially
contributed to their hosts' evolution by providing novel regulatory or coding sequences. We …

Transposable element exaptation into regulatory regions is rare, influenced by evolutionary age, and subject to pleiotropic constraints

CN Simonti, M Pavličev, JA Capra - Molecular Biology and …, 2017 - academic.oup.com
Transposable element (TE)-derived sequences make up approximately half of most
mammalian genomes, and many TEs have been co-opted into gene regulatory elements …