Thrombosis remains a major problem in our society, manifesting across multiple
demographic groups and with high associated morbidity and mortality. Thrombus …

Recent studies have demonstrated a role of neutrophils in both venous and arterial
thrombosis. A key prothrombotic feature of neutrophils is their ability to release web-like …

Innate immunity and blood coagulation are evolutionary entangled in an intricate network of
molecular and cellular interactions, thus forming an integral part of the host-defense system …

Recent advances in pharmacotherapy have markedly improved the prognosis of
cardiovascular disease (CVD) but have not completely conquered it. Therapies targeting the …

Neutrophils recognize particulate substrates of microbial or endogenous origin and react by
sequestering the cargo via phagocytosis or by releasing neutrophil extracellular traps …

Thrombotic complications are still a major health risk worldwide. Our view on the
pathophysiology of thrombosis has significantly changed since the discovery of neutrophil …

Thrombotic events, both arterial and venous, are a major health concern worldwide. Further,
autoimmune diseases, such as systemic lupus erythematosus, anti-neutrophil cytoplasmic …

Thrombotic diseases seriously endanger human health, neutrophils and neutrophil
extracellular traps (NETs) play an important role in abnormal thrombus formation. NETs are …

Neutrophils play a vital role in the formation of arterial, venous and cancer-related
thrombosis. Recent studies have shown that in a process known as NETosis, neutrophils …

Nearly 15 years after the first description of neutrophil extracellular traps (NETs), our
knowledge concerning this structure has expanded considerably. Initially, NETs were …