Epigenome-wide association study in Chinese monozygotic twins identifies DNA methylation loci associated with blood pressure
W Wang, J Yao, W Li, Y Wu, H Duan, C Xu, X Tian… - Clinical …, 2023 - Springer
Background Hypertension is a crucial risk factor for developing cardiovascular disease and
reducing life expectancy. We aimed to detect DNA methylation (DNAm) variants potentially …
reducing life expectancy. We aimed to detect DNA methylation (DNAm) variants potentially …
Association between DNA methylation and blood pressure: a 5-year longitudinal twin study
Background: Previous EWASs (Epigenome-Wide Association Studies) have reported
hundreds of blood pressure (BP) associated 5′-cytosine-phosphate-guanine-3′(CpG) …
hundreds of blood pressure (BP) associated 5′-cytosine-phosphate-guanine-3′(CpG) …
Identification, heritability, and relation with gene expression of novel DNA methylation loci for blood pressure
We conducted an epigenome-wide association study meta-analysis on blood pressure (BP)
in 4820 individuals of European and African ancestry aged 14 to 69. Genome-wide DNA …
in 4820 individuals of European and African ancestry aged 14 to 69. Genome-wide DNA …
Associations between high blood pressure and DNA methylation
Background High blood pressure is a major risk factor for cardiovascular disease and is
influenced by both environmental and genetic factors. Epigenetic processes including DNA …
influenced by both environmental and genetic factors. Epigenetic processes including DNA …
Unique associations of DNA methylation regions with 24-hour blood pressure phenotypes in black participants
Background: Epigenetic marks (eg, DNA methylation) may capture the effect of gene-
environment interactions. DNA methylation is involved in blood pressure (BP) regulation and …
environment interactions. DNA methylation is involved in blood pressure (BP) regulation and …
The interplay of epigenetic, genetic, and traditional risk factors on blood pressure: findings from the health and retirement study
The epigenome likely interacts with traditional and genetic risk factors to influence blood
pressure. We evaluated whether 13 previously reported DNA methylation sites (CpGs) are …
pressure. We evaluated whether 13 previously reported DNA methylation sites (CpGs) are …
Epigenome-wide analysis of DNA methylation and coronary heart disease: a nested case-control study
Background: Identifying environmentally responsive genetic loci where DNA methylation is
associated with coronary heart disease (CHD) may reveal novel pathways or therapeutic …
associated with coronary heart disease (CHD) may reveal novel pathways or therapeutic …
DNA methylation modules associate with incident cardiovascular disease and cumulative risk factor exposure
Background Epigenome-wide association studies using DNA methylation have the potential
to uncover novel biomarkers and mechanisms of cardiovascular disease (CVD) risk …
to uncover novel biomarkers and mechanisms of cardiovascular disease (CVD) risk …
DNA methylation analysis identifies loci for blood pressure regulation
Genome-wide association studies have identified hundreds of genetic variants associated
with blood pressure (BP), but sequence variation accounts for a small fraction of the …
with blood pressure (BP), but sequence variation accounts for a small fraction of the …
Impact of tobacco, alcohol, and marijuana on genome-wide DNA methylation and its relationship with hypertension
Tobacco, alcohol, and marijuana consumption is an important public health problem
because of their high use worldwide and their association with the risk of mortality and many …
because of their high use worldwide and their association with the risk of mortality and many …