Transdermal Delivery of Drug-Loaded Nanocarriers Using Solid Microneedles

B Newell, W Zhan - Available at SSRN 4677256, 2023 - papers.ssrn.com
Solid microneedles can successfully puncture the stratum corneum and thus enable the
drugs to migrate from the adhesive patch to the viable skin tissues for therapy. The treatment …

Numerical Simulation of Transdermal Delivery of Drug Nanocarriers Using Solid Microneedles

B Newell, W Zhan - bioRxiv, 2023 - biorxiv.org
Solid microneedles can successfully puncture the stratum corneum and thus enable the
drugs to migrate from the adhesive patch to the viable skin tissues for therapy. The treatment …

[HTML][HTML] Numerical simulation of transdermal delivery of drug nanocarriers using solid microneedles and medicated adhesive patch

BB Newell, W Zhan - International Journal of Heat and Mass Transfer, 2024 - Elsevier
Solid microneedles can successfully puncture the stratum corneum and thus enable the
drugs to travel from the adhesive patch to the viable skin tissues for therapy. The treatment in …

[HTML][HTML] Mathematical modelling of microneedle-mediated transdermal delivery of drug nanocarriers into skin tissue and circulatory system

B Newell, W Zhan - Journal of Controlled Release, 2023 - Elsevier
Microneedle-mediated transdermal delivery using nanocarriers can successfully overcome
the barrier of the stratum corneum and protect drugs from elimination in skin tissues …

Microneedle-mediated transdermal nanodelivery systems: a review

S Ruan, Y Zhang, N Feng - Biomaterials Science, 2021 - pubs.rsc.org
The greatest limitation in the development of transdermal drug delivery systems is that only a
few drugs can permeate the skin due to the barrier function of the stratum corneum. Active …

[PDF][PDF] Microneedle: Recent Advancements In Transdermal Drug Delivery System

B Patel, F Parekh, DPP Krupa Vyas - pnrjournal.com
Due to its reduced invasiveness, low rejection rate, and remarkable ease of administration,
transdermal drug delivery (TDD) has recently become a viable alternative to oral and …

Microneedles for Transdermal Drug Delivery: A Systematic Review

DR Suryabhan, AS Balasaheb - International Journal of …, 2022 - ijpsnonline.com
Transdermal delivery has the benefit of bypassing the first-pass effect and allowing for long-
term drug release. The stratum corneum (SC), on the other hand, creates a barrier, which …

Microneedle-based drug delivery systems for transdermal route

M Bernadete Riemma Pierre… - Current drug …, 2014 - ingentaconnect.com
Transdermal delivery offers an attractive, noninvasive administration route but it is limited by
the skin's barrier to penetration. Minimally invasive techniques, such as the use of …

Microneedles-based transdermal drug delivery systems: a review

Y Hao, W Li, XL Zhou, F Yang… - Journal of biomedical …, 2017 - ingentaconnect.com
A microneedle (MN) is a micron-sized needle with a height of 10–2000 μm and a width of 10–
50 μm, which can penetrate through the epidermis layer to dermal tissue directly without …

Modelling transdermal drug delivery using microneedles: Effect of geometry on drug transport behaviour

O Olatunji, DB Das, V Nassehi - Journal of pharmaceutical sciences, 2012 - Elsevier
Transdermal drug delivery using microneedles (MNs) depends on the rate of drug transport
through the viable epidermis. Therefore, minimising the distance between the drug-loaded …