Made in the womb: maternal programming of offspring cardiovascular function by an obesogenic womb
Obesity incidence has been increasing at an alarming rate, especially in women of
reproductive age. It is estimated that 50% of pregnancies occur in overweight or obese …
reproductive age. It is estimated that 50% of pregnancies occur in overweight or obese …
Programming by maternal obesity: a pathway to poor cardiometabolic health in the offspring
I Inzani, SE Ozanne - Proceedings of the Nutrition Society, 2022 - cambridge.org
There is an ever increasing prevalence of maternal obesity worldwide such that in many
populations over half of women enter pregnancy either overweight or obese. This review …
populations over half of women enter pregnancy either overweight or obese. This review …
Maternal obesity: A focus on maternal interventions to improve health of offspring
A Shrestha, M Prowak, VM Berlandi-Short… - Frontiers in …, 2021 - frontiersin.org
Maternal obesity has many implications for offspring health that persist throughout their
lifespan that include obesity and cardiovascular complications. Several different factors …
lifespan that include obesity and cardiovascular complications. Several different factors …
The Endocrine–Metabolic Axis Regulation in Offspring Exposed to Maternal Obesity—Cause or Consequence in Metabolic Disease Programming?
Obesity incidence is rising worldwide, including women of reproductive age, contributing to
increased gestations in which Maternal Obesity (MO) occurs. Offspring born to obese …
increased gestations in which Maternal Obesity (MO) occurs. Offspring born to obese …
Impact of maternal obesity on fetal programming of cardiovascular disease
VHJ Roberts, AE Frias, KL Grove - Physiology, 2015 - journals.physiology.org
The in utero environment is a key determinant of long-term health outcomes; poor maternal
metabolic state and placental insufficiency are strongly associated with these long-term …
metabolic state and placental insufficiency are strongly associated with these long-term …
A maternal high-fat, high-sucrose diet induces transgenerational cardiac mitochondrial dysfunction independently of maternal mitochondrial inheritance
JLA Ferey, AL Boudoures, M Reid… - American Journal …, 2019 - journals.physiology.org
Maternal obesity is correlated with cardiovascular disease in offspring, with a 1.3-fold
increase in events observed in offspring of obese women. We have observed that obesity …
increase in events observed in offspring of obese women. We have observed that obesity …
Maternal diet-induced obesity programmes cardiac dysfunction in male mice independently of post-weaning diet
E Loche, HL Blackmore, AA Carpenter… - Cardiovascular …, 2018 - academic.oup.com
Aims Obesity during pregnancy increases risk of cardiovascular disease (CVD) in the
offspring and individuals exposed to over-nutrition during fetal life are likely to be exposed to …
offspring and individuals exposed to over-nutrition during fetal life are likely to be exposed to …
The epidemiology and mechanisms of lifetime cardiopulmonary morbidities associated with pre-pregnancy obesity and excessive gestational weight gain
S Rastogi, D Rastogi - Frontiers in cardiovascular medicine, 2022 - frontiersin.org
Obesity has reached pandemic proportions in the last few decades. The global increase in
obesity has contributed to an increase in the number of pregnant women with pre-pregnancy …
obesity has contributed to an increase in the number of pregnant women with pre-pregnancy …
Maternal obesity, lipotoxicity and cardiovascular diseases in offspring
M Dong, Q Zheng, SP Ford, PW Nathanielsz… - Journal of Molecular and …, 2013 - Elsevier
Maternal obesity has risen dramatically over the past 20years, by nearly 42% in African-
Americans and 29% in Caucasians. Maternal obesity is afflicted with many maternal …
Americans and 29% in Caucasians. Maternal obesity is afflicted with many maternal …
Maternal diet-induced obesity and offspring cardiovascular health
HL Blackmore, SE Ozanne - … of developmental origins of health and …, 2013 - cambridge.org
It is widely recognized that environmental insults during adulthood including smoking, lack
of exercise and a poor diet increases an individual's risk of cardiovascular disease (CVD) …
of exercise and a poor diet increases an individual's risk of cardiovascular disease (CVD) …