IgG from patients with mild or severe COVID‑19 reduces the frequency and modulates the function of peripheral mucosal-associated invariant T cells in PBMCs from …

NR Machado, BO Fagundes… - Biomedical …, 2023 - spandidos-publications.com
Lower levels of peripheral mucosal‑associated invariant T (MAIT) cells have been observed
in the peripheral blood of patients with severe coronavirus disease 2019 (COVID‑19) …

Mucosal-associated invariant T (MAIT) cells are highly activated and functionally impaired in COVID-19 patients

S Deschler, J Kager, J Erber, L Fricke, P Koyumdzhieva… - Viruses, 2021 - mdpi.com
Coronavirus disease 2019 (COVID-19), caused by infection with severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2), comprises mild courses of disease as well as …

[HTML][HTML] Mucosal-associated invariant T cells as a possible target to suppress secondary infections at COVID-19

RA Akasov, EV Khaydukov - Frontiers in immunology, 2020 - frontiersin.org
Co-infections are of proven importance in the severity of respiratory diseases while their
involvement in COVID-19 progression is still little discussed (1). However, one in seven …

[HTML][HTML] Mucosal-Associated Invariant T Cells are not susceptible in vitro to SARS-CoV-2 infection but accumulate into the lungs of COVID-19 patients

X Huang, J Kantonen, K Nowlan, NA Nguyen… - Virus Research, 2024 - Elsevier
Prolonged T cell lymphopenia is common in COVID-19, caused by SARS-CoV-2. While the
mechanisms of lymphopenia during COVID-19 remain elusive, it is especially pronounced in …

Dynamic MAIT Cell Recovery after Severe COVID-19 Is Transient with Signs of Heterogeneous Functional Anomalies

T Kammann, JB Gorin, T Parrot, Y Gao… - The Journal of …, 2024 - journals.aai.org
Mucosal-associated invariant T (MAIT) cells are an abundant population of unconventional T
cells in humans and play important roles in immune defense against microbial infections …

Activation and functional alteration of mucosal-associated invariant T cells in adult patients with community-acquired pneumonia

L Ouyang, M Wu, Z Shen, X Cheng, W Wang… - Frontiers in …, 2021 - frontiersin.org
Community-acquired pneumonia (CAP) remains the significant infectious cause of morbidity
and mortality worldwide. Although mucosal-associated invariant T cells (MAIT) play roles in …

of article: mucosal-associated invariant T cells in lung diseases

X Wen, X Zhang, S Nian, G Wei, X Guo, H Yu… - International …, 2021 - Elsevier
The lungs are directly connected to the external environment, which makes them more
vulnerable to infection and injury. They are protected by the respiratory epithelium and …

[HTML][HTML] Single-cell transcriptomic profiling of MAIT cells in patients with COVID-19

J Shi, J Zhou, X Zhang, W Hu, JF Zhao… - Frontiers in …, 2021 - frontiersin.org
Background Mucosal-associated invariant T (MAIT) cells are considered to participate of the
host immune response against acute severe acute respiratory syndrome coronavirus 2 …

Suppressive monocytes impair MAIT cells response via IL-10 in patients with severe COVID-19

Q Yang, Y Wen, F Qi, X Gao, W Chen, G Xu… - The Journal of …, 2021 - journals.aai.org
Immune cell responses are strikingly altered in patients with severe coronavirus disease
2019 (COVID-19), but the immunoregulatory process in these individuals is not fully …

MAIT cells in COVID-19: heroes, villains, or both?

SMM Haeryfar - Critical Reviews™ in Immunology, 2020 - dl.begellhouse.com
Mucosa-associated invariant T cells (MAIT cells) are unconventional, innate-like T
lymphocytes with remarkable effector and immunoregulatory functions. They are abundant …