Our skin has a unique barrier function, which is imperative for the body's protection against
external pathogens and environmental insults. Although interacting closely and sharing …

Our skin is the interface through which we mediate lifelong interactions with our surrounding
environment. Initial development of the skin's epidermis, adnexal structures, and barrier …

The skin of preterm infants is a delicate organ with critical structural and functional
differences as compared to term born infants. Unique features contribute to an increased …

Establishment of a well‐functioning immune network in skin is crucial for its barrier function.
This begins in utero alongside the structural differentiation and maturation of skin, and …

Recent focus on the neonatal intestinal microbiome has advanced our knowledge of the
complex interplay between the intestinal barrier, the developing immune system, and …

The fascinating story of epidermal immunity begins in-utero where the epidermal barrier
derives from ectoderm, evolves through carefully orchestrated biological processes …

Background Early‐life microbial colonization of the skin may modulate the immune system
and impact the development of atopic dermatitis (AD) and allergic diseases later in life. To …

As human skin hosts a diverse microbiota in health and disease, there is an emerging
consensus that dysregulated interactions between host and microbiome may contribute to …

Our skin contributes critically to health via its role as a barrier tissue, carefully regulating
passage of key substrates while also providing defense against exogenous threats …

Within days after birth, rapid surface colonization of infant skin coincides with significant
functional changes. Gradual maturation of skin function, structure, and composition …