Stabilization of hemorrhage and resuscitation is priority in trauma-induced coagulopathy
treatment. Alternative products such as tranexamic acid, recombinant factors, prothrombic …

Trauma-induced coagulopathy is a primary factor in many trauma-related fatalities.
Management hinges upon rapid diagnosis of coagulation abnormalities and immediate …

Hemorrhage remains a major cause of potentially preventable deaths. Trauma and massive
transfusion are associated with coagulopathy secondary to tissue injury, hypoperfusion …

Abstract Purpose of Review Scientific findings continue to advance the field of resuscitation
and management of bleeding and coagulopathy in civilian patients with acute trauma …

Hemorrhage in the setting of severe trauma is a leading cause of death worldwide. The
pathophysiology of hemorrhage and coagulopathy in severe trauma is complex and remains …

Trauma associated with massive bleeding carries a high mortality even in the setting of early
care in a trauma center. Such patients develop a significant coagulopathy soon after injury …

Current evidence in trauma resuscitation indicates a potential role for coagulation factor
concentrates and other haemostatic agents in correcting trauma-induced coagulopathy …

The collective of trauma patients is heterogeneous. Despite the lack of evidence, there are
strong arguments for individualized patient treatment with coagulation factors for some …

Trauma is the most common cause of death in the young and hemorrhage is the most
important cause of death in patients with trauma. Recently redefined pathways of …

Trauma promotes trauma‐induced coagulopathy, which requires urgent treatment with fixed‐
ratio transfusions of red blood cells, fresh frozen plasma and platelet concentrates, or goal …