[HTML][HTML] Fibroblast growth factor 10 reverses cigarette smoke-and elastase-induced emphysema and pulmonary hypertension in mice
Background COPD is an incurable disease and a leading cause of death worldwide. In
mice, fibroblast growth factor (FGF) 10 is essential for lung morphogenesis, and in humans …
mice, fibroblast growth factor (FGF) 10 is essential for lung morphogenesis, and in humans …
[HTML][HTML] The role of FGF-2 in smoke-induced emphysema and the therapeutic potential of recombinant FGF-2 in patients with COPD
YS Kim, G Hong, DH Kim, YM Kim, YK Kim… - … & molecular medicine, 2018 - nature.com
Although the positive effects of recombinant fibroblast growth factor-2 (rFGF-2) in chronic
obstructive pulmonary disease (COPD) have been implicated in previous studies …
obstructive pulmonary disease (COPD) have been implicated in previous studies …
[HTML][HTML] FGF signaling in lung development and disease: human versus mouse
S Danopoulos, J Shiosaki, D Al Alam - Frontiers in genetics, 2019 - frontiersin.org
Fibroblast growth factor 10 (FGF10) plays an important role in mouse lung development,
injury, and repair. It is considered the main morphogen driving lung branching …
injury, and repair. It is considered the main morphogen driving lung branching …
[HTML][HTML] Fibroblast growth factor 10 attenuates chronic obstructive pulmonary disease by protecting against glycocalyx impairment and endothelial apoptosis
T Jiang, W Hu, S Zhang, C Ren, S Lin, Z Zhou… - Respiratory …, 2022 - Springer
Background The defects and imbalance in lung repair and structural maintenance contribute
to the pathogenesis of chronic obstructive pulmonary diseases (COPD), yet the molecular …
to the pathogenesis of chronic obstructive pulmonary diseases (COPD), yet the molecular …
Cigarette smoke induces growth differentiation factor 15 production in human lung epithelial cells: implication in mucin over-expression
Q Wu, D Jiang, HW Chu - Innate immunity, 2012 - journals.sagepub.com
Excessive mucus is a hallmark of chronic obstructive pulmonary disease (COPD). There is
an emerging interest in the role of TGF-β signaling in the initiation and progression of COPD …
an emerging interest in the role of TGF-β signaling in the initiation and progression of COPD …
[HTML][HTML] FGF10 and human lung disease across the life spectrum
LS Prince - Frontiers in genetics, 2018 - frontiersin.org
Lung diseases impact patients across the lifespan, from infants in the first minutes of life
through the aged population. Congenital abnormalities of lung structure can cause lung …
through the aged population. Congenital abnormalities of lung structure can cause lung …
[HTML][HTML] FGF21 attenuates pulmonary fibrogenesis through ameliorating oxidative stress in vivo and in vitro
S Zhang, D Yu, M Wang, T Huang, H Wu… - Biomedicine & …, 2018 - Elsevier
Pulmonary fibrosis (PF) is a chronic, progressive lung disease, characterized by excessive
matrix formation, destruction of the normal lung architecture, dysfunction and finally death …
matrix formation, destruction of the normal lung architecture, dysfunction and finally death …
[HTML][HTML] Good things come in 2s: Type 2 alveolar epithelial cells and fibroblast growth factor receptor 2
C Shimbori, E El Agha - American Journal of Respiratory Cell and …, 2020 - atsjournals.org
Idiopathic pulmonary fibrosis (IPF) is the most common form of idiopathic interstitial
pneumonia and the most aggressive form of diffuse parenchymal lung disease …
pneumonia and the most aggressive form of diffuse parenchymal lung disease …
FGF19 is downregulated in idiopathic pulmonary fibrosis and inhibits lung fibrosis in mice
A Justet, M Ghanem, T Boghanim… - American Journal of …, 2022 - atsjournals.org
Idiopathic pulmonary fibrosis (IPF) is a devastating lung disease with limited therapeutic
possibilities. FGF19 (fibroblast growth factor 19), an endocrine FGF, was recently shown to …
possibilities. FGF19 (fibroblast growth factor 19), an endocrine FGF, was recently shown to …
[HTML][HTML] Elevated GDF-15 contributes to pulmonary inflammation upon cigarette smoke exposure
FM Verhamme, LJM Seys, EG De Smet, S Provoost… - Mucosal …, 2017 - Elsevier
The molecular mechanisms underlying the pathogenesis of chronic obstructive pulmonary
disease (COPD) are still unclear, however signaling pathways associated with lung …
disease (COPD) are still unclear, however signaling pathways associated with lung …