With the aging of the world population, there has been a notable increase in the incidence of
Alzheimer disease (AD), the most prevalent neurodegenerative disease affecting the elderly …

Environmental enrichment (EE) is an environmental paradigm encompassing sensory,
cognitive, and physical stimulation at a heightened level. Previous studies have reported the …

Aging-associated brain changes include functional alterations that are usually related with
memory decline. Epidemiological reports show that a physically and intellectually active life …

Environmental enrichment (EE) has been shown to improve cognitive performance and
brain indices of cognition in normal mice and rats. Because the therapeutic potential of …

Although social, physical, and cognitive activities have each been suggested to reduce the
risk of Alzheimer's disease (AD), epidemiologic studies cannot determine which activity or …

Environmental enrichment (EE) is a process of brain stimulation by modifying the
surroundings, for example, by changing the sensory, social, or physical conditions. Rodents …

The main aim of this chapter is to review preclinical studies that have evaluated
interventions which may aid in preventing or delaying age-related behavioural decline …

Aging entails a progressive decline of cognitive abilities. However, since the brain is
endowed with considerable plasticity, adequate stimulation can delay or partially …

Brain aging is characterized by global changes which are thought to underlie age-related
cognitive decline. These include variations in brain activity and the progressive increase in …

Background: In recent decades, the interest in behavioral interventions has been growing
due to the higher prevalence of age-related cognitive impairments. Hence, behavioral …