Efeitos da exposição a baixas doses de pilocarpina e ao crack sobre sistema de enzimas antioxidantes

MMJH Reiter - 2023 - repositorio.ufal.br
O crack é um estimulante do sistema nervoso central (SNC) feito a partir da cocaína, que é
extraída das folhas de Erythroxylon coca (BAHLS et al., 2002). Para obtenção do crack, é …

[HTML][HTML] O papel da dieta cetogênica no estresse oxidativo presente na epilepsia experimental

TKC Gomes, SL Oliveira, TR Ataíde… - Journal of Epilepsy …, 2011 - SciELO Brasil
INTRODUÇÃO: A epilepsia é um dos transtornos neurológicos mais comuns, sendo
definido como uma condição de crises recorrentes espontâneas. Existe uma importante …

[HTML][HTML] Inhibitory action of antioxidants (ascorbic acid or α-tocopherol) on seizures and brain damage induced by pilocarpine in rats

AR Tomé, PMP Ferreira, RM Freitas - Arquivos de Neuro-Psiquiatria, 2010 - SciELO Brasil
Temporal lobe epilepsy is the most common form of epilepsy in humans. Oxidative stress is
a mechanism of cell death induced by seizures. Antioxidant compounds have …

The role of the ketogenic diet on oxidative stress present in experimental epilepsy

TKC Gomes, SL Oliveira, TR Ataíde… - Journal of Epilepsy …, 2011 - SciELO Brasil
INTRODUÇÃO: A epilepsia é um dos transtornos neurológicos mais comuns, sendo
definido como uma condição de crises recorrentes espontâneas. Existe uma importante …

Oxidative stress in epileptogenesis: Febrile seizures, chemoconvulsant pilocarpine, and electrical stimulation

DAL Navarro, M Crespo, M Martín - Oxidative Stress and Dietary …, 2020 - Elsevier
Epileptogenesis is characterized by progressive functional and structural alterations in
certain cerebral regions, leading to the appearance of spontaneous recurrent seizures …

Antioxidant Treatments: Effect on Behaviour, Histopathological and Oxidative Stress in Epilepsy Model

RM de Freitas - Edited by Amit Agrawal, 2012 - books.google.com
The aim of this chapter is to describe several studies which have attempted to
measure/detect effects of antioxidant compounds (lipoic acid, ubiquinone, ascorbic acid and …

Antioxidant response and oxidative damage in brain cortex after high dose of pilocarpine

S Tejada, A Sureda, C Roca, A Gamundi… - Brain research bulletin, 2007 - Elsevier
Pilocarpine is a cholinergic agonist capable to induce seizures and an epilepticus-like state
in rodents. This status epilepticus (SE) is an useful animal model to study the development …

Oxidative stress in the hippocampus during experimental seizures can be ameliorated with the antioxidant ascorbic acid

ÍMS Santos, AR Tomé, GB Saldanha… - Oxidative medicine …, 2009 - Wiley Online Library
Ascorbic acid has many nonenzymatic actions and is a powerful water‐soluble antioxidant. It
protects low density lipoproteins from oxidation and reduces harmful oxidants in the central …

Seizures, antiepileptics, antioxidants and oxidative stress: an insight for researchers

PU Devi, A Manocha, D Vohora - Expert opinion on …, 2008 - Taylor & Francis
Background: Neuronal hyperexcitability and excessive production of free radicals have been
implicated in the pathogenesis of a considerable range of neurological disorders, including …

Acute seizure activity promotes lipid peroxidation, increased nitrite levels and adaptive pathways against oxidative stress in the frontal cortex and striatum

HVN Júnior, MMF Fonteles… - … medicine and cellular …, 2009 - Wiley Online Library
Previous experiments have shown that the generation of free radicals in rat brain
homogenates is increased following pilocarpine‐induced seizures and status epilepticus …