Metabolic engineering of thermophilic Bacillus methanolicus for riboflavin overproduction from methanol
VJ Klein, LF Brito, F Perez‐Garcia… - Microbial …, 2023 - Wiley Online Library
The growing need of next generation feedstocks for biotechnology spurs an intensification of
research on the utilization of methanol as carbon and energy source for biotechnological …
research on the utilization of methanol as carbon and energy source for biotechnological …
[HTML][HTML] Biotechnological strategies of riboflavin biosynthesis in microbes
Riboflavin is an essential micronutrient for humans and must be obtained exogenously from
foods or supplements. Numerous studies have suggested a major role of riboflavin in the …
foods or supplements. Numerous studies have suggested a major role of riboflavin in the …
Metabolic engineering of Escherichia coli for the production of riboflavin
Z Lin, Z Xu, Y Li, Z Wang, T Chen, X Zhao - Microbial cell factories, 2014 - Springer
Abstract Background Riboflavin (vitamin B 2), the precursor of the flavin cofactors flavin
mononucleotide (FMN) and flavin adenine dinucleotide (FAD), is used commercially as an …
mononucleotide (FMN) and flavin adenine dinucleotide (FAD), is used commercially as an …
Metabolic engineering of Bacillus subtilis for enhancing riboflavin production by alleviating dissolved oxygen limitation
J You, C Yang, X Pan, M Hu, Y Du, T Osire, T Yang… - Bioresource …, 2021 - Elsevier
Riboflavin, an essential vitamin for animals, is used widely in the pharmaceutical industry
and as a food and feed additive. The microbial synthesis of riboflavin requires a large …
and as a food and feed additive. The microbial synthesis of riboflavin requires a large …
Metabolic engineering of Corynebacterium glutamicum for methanol metabolism
S Witthoff, K Schmitz, S Niedenführ, K Nöh… - Applied and …, 2015 - Am Soc Microbiol
Methanol is already an important carbon feedstock in the chemical industry, but it has found
only limited application in biotechnological production processes. This can be mostly …
only limited application in biotechnological production processes. This can be mostly …
Engineering thermophilic Geobacillus thermoglucosidasius for riboflavin production
The potential advantages for fermentation production of chemicals at high temperatures are
attractive, such as promoting the rate of biochemical reactions, reducing the risk of …
attractive, such as promoting the rate of biochemical reactions, reducing the risk of …
Microbial production of riboflavin: biotechnological advances and perspectives
J You, X Pan, C Yang, Y Du, T Osire, T Yang… - Metabolic …, 2021 - Elsevier
Riboflavin is an essential nutrient for humans and animals, and its derivatives flavin
mononucleotide (FMN) and flavin adenine dinucleotide (FAD) are cofactors in the cells …
mononucleotide (FMN) and flavin adenine dinucleotide (FAD) are cofactors in the cells …
Constructing a methanol-dependent Bacillus subtilis by engineering the methanol metabolism
Methanol is a promising green feedstock for producing fuels and chemicals because it is
inexpensive, clean, environmentally friendly, and easily prepared. Thus, many studies have …
inexpensive, clean, environmentally friendly, and easily prepared. Thus, many studies have …
Lactic acid bacteria as a cell factory for riboflavin production
Consumers are increasingly becoming aware of their health and nutritional requirements,
and in this context, vitamins produced in situ by microbes may suit their needs and …
and in this context, vitamins produced in situ by microbes may suit their needs and …
Plasmid-Dependent Methylotrophy in Thermotolerant Bacillus methanolicus
T Brautaset, ØM Jakobsen, MC Flickinger… - Journal of …, 2004 - Am Soc Microbiol
Bacillus methanolicus can efficiently utilize methanol as a sole carbon source and has an
optimum growth temperature of 50° C. With the exception of mannitol, no sugars have been …
optimum growth temperature of 50° C. With the exception of mannitol, no sugars have been …
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