[HTML][HTML] The Impact of p70S6 Kinase-Dependent Phosphorylation of Gemin2 in UsnRNP Biogenesis

LM Esser, Q Li, M Jüdt, T Kähne, B Stork… - International Journal of …, 2023 - mdpi.com
The survival motor neuron (SMN) complex is a multi-megadalton complex involved in post-
transcriptional gene expression in eukaryotes via promotion of the biogenesis of uridine-rich …

Phosphoregulation of the human SMN complex

A Husedzinovic, F Oppermann… - European Journal of …, 2014 - Elsevier
The survival motor neuron (SMN) complex is a macromolecular machine comprising 9 core
proteins: SMN, Gemins2–8 and unrip in vertebrates. It performs tasks in RNA metabolism …

SMN-A chaperone for nuclear RNP social occasions?

AC Raimer, KM Gray, AG Matera - RNA biology, 2017 - Taylor & Francis
ABSTRACT Survival Motor Neuron (SMN) protein localizes to both the nucleus and the
cytoplasm. Cytoplasmic SMN is diffusely localized in large oligomeric complexes with core …

[HTML][HTML] Gemin8 is a novel component of the survival motor neuron complex and functions in small nuclear ribonucleoprotein assembly

C Carissimi, L Saieva, J Baccon, P Chiarella… - Journal of biological …, 2006 - ASBMB
The survival motor neuron (SMN) protein is the product of the spinal muscular atrophy
disease gene. SMN and Gemin2–7 proteins form a large macromolecular complex that …

[HTML][HTML] Dephosphorylation of survival motor neurons (SMN) by PPM1G/PP2Cγ governs Cajal body localization and stability of the SMN complex

S Petri, M Grimmler, S Over, U Fischer… - The Journal of cell …, 2007 - ncbi.nlm.nih.gov
The survival motor neuron (SMN) complex functions in maturation of uridine-rich small
nuclear ribonucleoprotein (RNP) particles. SMN mediates the cytoplasmic assembly of Sm …

[HTML][HTML] A comprehensive interaction map of the human survival of motor neuron (SMN) complex

S Otter, M Grimmler, N Neuenkirchen, A Chari… - Journal of Biological …, 2007 - ASBMB
Assembly of the Sm-class of U-rich small nuclear ribonucleoprotein particles (U snRNPs) is
a process facilitated by the macromolecular survival of motor neuron (SMN) complex. This …

[HTML][HTML] Role of survival motor neuron complex components in small nuclear ribonucleoprotein assembly

C Ogawa, K Usui, F Ito, M Itoh, Y Hayashizaki… - Journal of Biological …, 2009 - ASBMB
Survival motor neuron (SMN) complex is essential for the biogenesis of the small nuclear
ribonucleoprotein (snRNP) complex, although the complete role of each SMN complex …

Gemin4 is an essential gene in mice, and its overexpression in human cells causes relocalization of the SMN complex to the nucleoplasm

ID Meier, MP Walker, AG Matera - Biology open, 2018 - journals.biologists.com
Gemin4 is a member of the Survival Motor Neuron (SMN) protein complex, which is
responsible for the assembly and maturation of Sm-class small nuclear ribonucleoproteins …

[HTML][HTML] Gemin8 is required for the architecture and function of the survival motor neuron complex

C Carissimi, L Saieva, F Gabanella… - Journal of Biological …, 2006 - ASBMB
The biogenesis of spliceosomal small nuclear ribonucleoproteins (snRNPs) in higher
eukaryotes requires the functions of several cellular proteins and includes nuclear as well as …

[HTML][HTML] SMN-independent subunits of the SMN complex: identification of a small nuclear ribonucleoprotein assembly intermediate

DJ Battle, M Kasim, J Wang, G Dreyfuss - Journal of Biological Chemistry, 2007 - ASBMB
The survival of motor neurons (SMN) complex is essential for the biogenesis of small
nuclear ribonucleoprotein (snRNP) complexes in eukaryotic cells. Reduced levels of SMN …