Despite colossal achievements in antibiotic therapy in recent decades, drug-resistant
pathogens have remained a leading cause of death and economic loss globally. One such …

An increased number of research articles in terms of infectious disease and multidrug
resistance challenges reveals that antibiotic resistance is becoming a serious health issue …

Multidrug resistance (MDR) to antibiotics presents a serious therapeutic problem in the
treatment of bacterial infections. The importance of this mechanism of resistance in clinical …

Bacterial drug resistance represents one of the most crucial problems in present day
antibacterial chemotherapy. Of particular concern to public health is the continuing …

For over 20 years, bacterial multidrug resistance (MDR) efflux pumps have been studied
because of their impact on resistance to antimicrobials. However, critical questions remain …

Salmonellae have evolved a wide range of molecular mechanisms to neutralize the effect of
antibiotics and evade the host immune system response. These mechanisms are exquisitely …

There are numerous genes in Salmonella enterica serovar Typhimurium that can confer
resistance to fluoroquinolone antibiotics, including those that encode topoisomerase …

Abstract Objectives In Gram-negative bacteria, drug susceptibility is associated with
multidrug efflux systems and an outer membrane (OM) barrier. Previous studies revealed …

Salmonella spp. is one of the most important foodborne pathogens. Typhoid fever and
enteritis caused by Salmonella enterica are associated with 16–33 million infections and …

Drug efflux systems play a major role in resistance to a wide range of noxious compounds in
several Gram negative species. Here, we report the drug resistance and virulence …