[PDF][PDF] Association between genetic polymorphisms in fibrinogen genes and bleeding risk in patients treated with direct oral anticoagulants

KH Choi, J Yee, TJ Song, J Park, HS Gwak - Ann Acad Med Singap, 2023 - annals.edu.sg
Introduction: This study aimed to investigate the association between polymorphisms in
fibrinogen genes and bleeding risk in patients receiving direct oral anticoagulants (DOACs) …

Association between genetic polymorphisms and bleeding in patients on direct oral anticoagulants

HY Yoon, TJ Song, J Yee, J Park, HS Gwak - Pharmaceutics, 2022 - mdpi.com
Objectives: The purpose of our study is to investigate the effects of apolipoprotein B (APOB)
and APOE gene polymorphisms on bleeding complications in patients receiving direct oral …

Genetic Factors of Renin–Angiotensin System Associated with Major Bleeding for Patients Treated with Direct Oral Anticoagulants

J Yee, TJ Song, HY Yoon, J Park, HS Gwak - Pharmaceutics, 2022 - mdpi.com
The purpose of this study was to identify the renin–angiotensin system (RAS)-related genetic
factors associated with bleeding and develop the bleeding risk scoring system in patients …

[PDF][PDF] Genetic Bleeding Risk Score (GBRS) for patients on oral anticoagulant therapy

R Nahar, IC Verma, R Deb, R Saxena… - … Journal of Genomic …, 2013 - sarkarimirror.com
Aims: The present study focussed on deriving and validating a 'genetic bleeding risk
score'(GBRS) based on genetic and non-genetic factors associated with bleeding in patients …

Construction of a risk scoring system using clinical factors and RYR2 polymorphisms for bleeding complications in patients on direct oral anticoagulants

EJ Jang, JS Kim, SA Choi, J Yee, TJ Song… - Frontiers in …, 2023 - frontiersin.org
Introduction: Bleeding is one of the most undesirable complications of direct oral
anticoagulants (DOACs). While the ryanodine receptor (RYR2) has been related to cardiac …

Polymorphisms in factor II and factor VII genes modulate oral anticoagulation with warfarin

RL D'Ambrosio, G D'Andrea, F Cappucci… - …, 2004 - haematologica.org
BACKGROUND AND OBJECTIVES: There is very considerable inter-individual variability in
warfarin dosages necessary to achieve target therapeutic anticoagulation. The variability is …

Exome-Wide Association Study of candidate pharmacogenes on DOAC haemorrhage

DA Sychev, AA Buianova, SP Abdullaev, KB Mirzaev… - 2024 - preprints.org
Background/Objectives: Direct oral anticoagulants (DOACs) are first-line medications for
stroke prevention in non-valvular atrial fibrillation (AF). However, variability in drug response …

[PDF][PDF] New Pharmacogenetic Markers to Predict the Risk of Bleeding During Taking of Direct Oral Anticoagulants

DA Kalinkin, AA Sokolova, DA Andreev, IN Sychev… - pdfs.semanticscholar.org
Aim. To search for new pharmacogenetic biomarkers of bleeding risk in patients taking
rivaroxaban and dabigatran for different indications: atrial fibrillation, endoprosthesis of large …

New pharmacogenetic markers to predict the risk of bleeding during taking of direct oral anticoagulants

KB Mirzaev, DV Ivashchenko, IV Volodin… - Rational …, 2020 - rpcardio.elpub.ru
Aim. To search for new pharmacogenetic biomarkers of bleeding risk in patients taking
rivaroxaban and dabigatran for different indications: atrial fibrillation, endoprosthesis of large …

Effect of Genotype on the Pharmacokinetics and Bleeding Events of Direct Oral Anticoagulants: A Systematic Review and Meta‐analysis

J Shi, T Wu, S Wu, X Chen, Q Ye… - The Journal of Clinical …, 2023 - Wiley Online Library
This meta‐analysis aimed to investigate the effect of the genotype on the pharmacokinetics
and bleeding events of direct oral anticoagulants (DOACs) and comprehensively searched …