Atherosclerosis is a dominant cause of cardiovascular disease. Accumulation of low-density
lipoproteins (LDL), formation of foam cells, and endothelial dysfunction within the arterial …

Atherosclerosis is a chronic inflammatory disease initiated by vascular inflammation and
monocyte recruitment in part. Diosgenin, a precursor of steroid hormones, has been shown …

The persistence of macrophage-derived foam cells in the artery wall fuels atherosclerosis
development. However, the mechanism of foam cell formation regulation remains elusive …

Atherosclerosis is one of the leading causes of death in patients with cardiovascular
diseases worldwide. Although some progress has been made in the treatment of …

Background Gal-geun-dang-gwi-tang (GGDGT), an herbal medicine, is used to treat
hypertension, stroke, and other inflammatory disorders in the clinical setting. Recently …

Dan-Shen-Yin (DSY) is a famous traditional Chinese formula. We determined its integrated
protective effects mechanisms of DSY in diabetic atherosclerosis rat model. DSY (5 or 10 …

One of characteristics of diabetes mellitus (DM) is endothelial cell (EC) dysfunction and
apoptosis which contributes to the development of vasculopathy. Advanced glycation end …

Abstract Rationale Diosgenin (Dgn), a structural analogue of cholesterol, has been reported
to have the hypolipidemic and antiatherogenic properties, but the underlying mechanisms …

Atherosclerosis (AS) is one of the major causes leading to mortality of dysfunctional
cardiovascular events in the menopausal women, which has long-term deficiency of …

Atherosclerosis results from accumulation of macrophages and extracellular matrix in the
arterial wall. Decorin, a small matrix proteoglycan, is able to regulate cell proliferation …