[HTML][HTML] Development of albumin monitoring system with hepatic hypoxia-on-a-chip

JY Kim, Y Han, BG Jeon, MS Nam, S Kwon, YJ Heo… - Talanta, 2023 - Elsevier
Hypoxia plays an essential role in the pathogenesis of various liver diseases, and albumin is
one of the important biomarkers secreted by the liver. In this study, we developed an …

Electrical impedimetric biosensors for liver function detection

YH Chuang, YT Chang, KL Liu, HY Chang… - Biosensors and …, 2011 - Elsevier
In this study, electrical impedimetric biosensors composed of Au-electrodes were fabricated
for the quantitative detection of human serum albumin (HSA), an essential biomarker of liver …

In vivo monitoring with micro-implantable hypoxia sensor based on tissue acidosis

S Dulay, L Rivas, S Miserere, L Pla, S Berdún, J Parra… - Talanta, 2021 - Elsevier
Hypoxia is a common medical problem, sometimes difficult to detect and caused by different
situations. Control of hypoxia is of great medical importance and early detection is essential …

Microphysiological system with continuous analysis of albumin for hepatotoxicity modeling and drug screening

A Asif, SH Park, AM Soomro, MAU Khalid… - Journal of Industrial and …, 2021 - Elsevier
In microfluidics, the emerging field of microphysiological systems (MPS) is overcoming the
challenge of physiological irrelevancy by animal models for drug discovery and …

A hydrogen peroxide biosensor based on direct electrochemistry of hemoglobin in Hb–Ag sol films

Y Xu, C Hu, S Hu - Sensors and Actuators B: Chemical, 2008 - Elsevier
Hemoglobin (Hb) was used as a template to fabricate hemoglobin–silver (Hb–Ag) sol in
which the hemoglobin showed direct electrochemistry on a glass carbon (GC) electrode …

Investigation of hemoglobin/gold nanoparticle heterolayer on micro-gap for electrochemical biosensor application

T Lee, TH Kim, J Yoon, YH Chung, JY Lee, JW Choi - Sensors, 2016 - mdpi.com
In the present study, we fabricated a hemoglobin/gold nanoparticle (Hb/GNP) heterolayer
immobilized on the Au micro-gap to confirm H2O2 detection with a signal-enhancement …

Denatured bovine serum albumin hydrogel–based electrochemical biosensors for detection of IgG

H Yang, Q Hou, C Ding - Microchimica Acta, 2022 - Springer
An antifouling sensing surface was constructed by crosslinking two-dimensional
nanomaterial MXene with bovine serum albumin (BSA) denatured by urea previously. The …

Online oxygen monitoring using integrated inkjet-printed sensors in a liver-on-a-chip system

A Moya, M Ortega-Ribera, X Guimerà, E Sowade… - Lab on a Chip, 2018 - pubs.rsc.org
The demand for real-time monitoring of cell functions and cell conditions has dramatically
increased with the emergence of organ-on-a-chip (OOC) systems. However, the …

Hydrogen peroxide biosensor based on a myoglobin/hydrophilic room temperature ionic liquid film

A Safavi, F Farjami - Analytical Biochemistry, 2010 - Elsevier
The composite film based on Nafion and hydrophilic room temperature ionic liquid (RTIL) 1-
butyl-3-methyl-imidazolium chloride ([bmim] Cl) was used as an immobilization matrix to …

State-of-the-art advancements in liver-on-a-chip (LOC): integrated biosensors for LOC

M Liu, Y Xiang, Y Yang, X Long, Z Xiao, Y Nan… - Biosensors and …, 2022 - Elsevier
Liver models are vital for the liver diseases and drug research as many novel drugs.
However, traditional liver models cannot meet this need, mainly because they cannot …